2021
DOI: 10.5493/wjem.v11.i5.66
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Abstract: Cardiovascular disease (CVD) has become one of the commonest causes of comorbidity and mortality among People living with human immunodeficiency virus (HIV) (PLWH) on antiretroviral therapy (ART). Nearly 50% of PLWH are likely to have an increased risk of developing CVD, including coronary heart disease, cerebrovascular disease, peripheral artery disease and aortic atherosclerosis. Aside from the common risk factors, HIV infection itself and side effects of antiretroviral therapy contribute to the pathophysiol… Show more

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Cited by 5 publications
(1 citation statement)
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“…In PLWH, immune activation and systemic inflammation appear to be caused by the translocation of microbial products from the gut mucosal surfaces to the peripheral blood. Microbial translocation could, potentially, lead to systemic inflammation [26]. Current research is focusing almost exclusively on the large intestine as the site of microbial product translocation to the blood [27][28][29], while other mucosal sites, such as the oral cavity, have rarely been studied.…”
Section: Introductionmentioning
confidence: 99%
“…In PLWH, immune activation and systemic inflammation appear to be caused by the translocation of microbial products from the gut mucosal surfaces to the peripheral blood. Microbial translocation could, potentially, lead to systemic inflammation [26]. Current research is focusing almost exclusively on the large intestine as the site of microbial product translocation to the blood [27][28][29], while other mucosal sites, such as the oral cavity, have rarely been studied.…”
Section: Introductionmentioning
confidence: 99%