2022
DOI: 10.4239/wjd.v13.i9.717
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Abstract: Oxidative stress, inflammation, and gut microbiota impairments have been implicated in the development and maintenance of diabetes mellitus. Strategies capable of recovering the community of commensal gut microbiota and controlling diabetes mellitus have increased in recent years. Some lactobacilli strains have an antioxidant and anti-inflammatory system capable of protecting against oxidative stress, inflammation, and diabetes mellitus. Experimental studies and some clinical trials have demonstrated that … Show more

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Cited by 10 publications
(3 citation statements)
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“…Treatment with DHI-V A P 2000 @CD markedly reversed these changes (Figure E-b and Supplemental Figure S13). The genus Limosilactobacillus , known for its positive modulation of the host antioxidant and anti-inflammatory system, showed a drastic decline in the BDL group, but its concentration were restored with DHI@CD, DHI-P 2000 @CD and DHI-V A P 2000 @CD treatments . Similar variations were observed in the genus Lactobacillus .…”
Section: Resultssupporting
confidence: 57%
“…Treatment with DHI-V A P 2000 @CD markedly reversed these changes (Figure E-b and Supplemental Figure S13). The genus Limosilactobacillus , known for its positive modulation of the host antioxidant and anti-inflammatory system, showed a drastic decline in the BDL group, but its concentration were restored with DHI@CD, DHI-P 2000 @CD and DHI-V A P 2000 @CD treatments . Similar variations were observed in the genus Lactobacillus .…”
Section: Resultssupporting
confidence: 57%
“…Transplantation of Lactobacillus can reduce inflammatory response. Lactobacillus and Parabacteroides were bacteria that can produce short-chain fatty acids (SCFAs) (43). SCFAs can enhance the autophagy of renal tubular cells and attenuate the renal fibrosis in diabetic mice (44).…”
Section: Discussionmentioning
confidence: 99%
“…Specifically, L. plantarum has been found to modulate human metabolism at the molecular, cellular, and population levels, leading to reduced blood glucose and lipids, regulated blood pressure, and ultimately decreased the incidence of CVD (Wang et al., 2022). Additionally, Limosilactobacillus fermentum exhibit antioxidant and anti‐inflammatory properties, effectively counteracting oxidative stress, inflammation, and diabetes (Lacerda et al., 2022). In vitro studies have suggested the capacity of probiotic interventions to inhibit the proliferation of cancer cells via the induction of apoptosis or cell cycle arrest (Mahmoudi et al., 2023; Thirabunyanon et al., 2009).…”
Section: Addition Of Dietary Supplements—diversification Of Functions...mentioning
confidence: 99%