Potential of sugarcane extracts as cosmetic and skincare ingredients

Carvalho, Maria João; Oliveira, Ana; Pedrosa, Sílvia Santos; Pintado, Manuela; Madureira, Ana Raquel

doi:10.1016/j.indcrop.2021.113625

Cited by 30 publications

(33 citation statements)

References 97 publications

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“…The phenolic compounds can be isolated, and their potential exploited for further food systems applications. The phenolic compounds profiles of several sugarcane byproducts have been characterized, mainly those of leaves, bagasse, and molasses, revealing the presence of flavones (luteolin, apigenin, and tricin derivatives), phenolic acids (sinapic, caffeic, and ferulic acids), and hydroxycinnamic acids [ 3 , 4 ]. However, sugarcane straw polyphenolic richness has not been well exploited, most likely because the straw residues were left in the fields to improve soil quality, increasing organic matter, water storage, control of weed infestation and, soil erosion, while reducing the amount of potassium and nitrogen fertilizers required.…”

Section: Introductionmentioning

confidence: 99%

Sugarcane Straw Polyphenols as Potential Food and Nutraceutical Ingredient

Oliveira¹,

Carvalho²,

Oliveira³

et al. 2022

Foods

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The sugarcane processing industry generates a large amount of straw, which has a negative environmental impact, and high costs are associated with their elimination, wasting their potential bioactive value attributed to their richness in polyphenols. In this study, an ethanolic extract produced from sugarcane straw was screened for its phenolic compounds content, and the potential use of this extract in the development of a food ingredient was further evaluated. Fifty different secondary metabolites belonging to the hydroxybenzoic acids, hydroxycinnamic acids, and flavonoids were identified by liquid chromatography–electrospray ionization–ultrahigh-resolution—quadrupole time of flight–mass spectrometry (LC-ESI-UHR-QqTOF-MS). The predominant phenolic compounds found were 4-hydroxybenzaldehyde, chlorogenic acid, and 5-O-feruloylquinic acid. The obtained extracts showed strong potential as food preservatives by exhibiting (a) antioxidant activity using both 2.2′-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt radical cation (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) methods; and (b) antimicrobial capacity, with a minimum inhibitory concentration of 50 mg/mL for Staphylococcus aureus, 74% inhibition for Bacillus cereus, and 44% for Salmonella enterica; and (c) the capacity to inhibit a food browning enzyme, tyrosinase (28–73% for 1–8 mg/ mL). Moreover, the extracts showed antidiabetic potential by inhibiting the enzymes α-glucosidase (15–38% for 1.25–5.00 mg/mL) and dipeptidyl peptidase-IV (DPP-IV) (62–114% for 0.31–5.00 mg/mL). The extract (0.625 mg/mL) also exhibited the capacity to reduce proinflammatory mediators (i.e., interleukins 6 and 8, and tumor necrosis factor alpha) when Caco-2 cells were stimulated with interleukin 1 beta. Thus, sugarcane straw extract, which is rich in phenolic compounds, showed high potential to be used in the development of food-preservative ingredients owing to its antioxidant and antimicrobial potential, and to be explored as a food supplement in diabetes prevention and as coadjuvant to reduce intestinal inflammation by reducing proinflammatory mediators.

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Section: Introductionmentioning

confidence: 99%

Sugarcane Straw Polyphenols as Potential Food and Nutraceutical Ingredient

Oliveira¹,

Carvalho²,

Oliveira³

et al. 2022

Foods

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“…Natural products have attracted interest as a new generation of cosmeceuticals. There is numerous evidence that plants possess a variety of active compounds, for example, terpenoids, alkaloids, and phenolic compounds [9][10][11]. Trigonella foenum-graecum L. (fenugreek), belonging to the family Leguminosae, is a herbaceous plant that typically grows in western Asia, northern India, Pharmaceuticals 2022, 15, 254 2 of 18 northern Africa, and the Mediterranean [12].…”

Section: Introductionmentioning

confidence: 99%

Ethanolic Fenugreek Extract: Its Molecular Mechanisms against Skin Aging and the Enhanced Functions by Nanoencapsulation

et al. 2022

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Fenugreek, or Trigonella foenum-graecum L. (family Leguminosae) seeds, are typically used as food supplements to increase postnatal lactation. Fenugreek extract displays antioxidative and anti-inflammatory properties, but its mechanisms against skin aging have not been exploited. In this research, we are the first to define an in vitro collagenase inhibitory activity of fenugreek extract (IC50 = 0.57 ± 0.02 mg/mL), which is 2.6 times more potent than vitamin C (IC50 = 1.46 mg/mL). Nanoencapsulation has been applied to improve the extract stability, and subsequently enhanced its bioactivities. Liponiosome encapsulating fenugreek extract (LNF) was prepared using a high-speed homogenizer, resulting in homogeneous spherical nanoparticles with sizes in the range of 174.7 ± 49.2 nm, 0.26 ± 0.04 in PdI, and 46.6 ± 7.4% of entrapment efficiency. LNF formulation significantly facilitated a sustained release and significantly enhanced skin penetration over the extracts, suggesting a potential use of LNF for transdermal delivery. The formulated LNF was highly stable, not toxic to human fibroblast, and was able to enhance cell viability, collagen production, and inhibit MMP1, MMP9, IL-6, and IL-8 secretions compared to the extract in the co-cultured skin model. Therefore, ethanolic fenugreek extract and its developed LNF display molecular mechanisms against skin aging and could potentially be used as an innovative ingredient for the prevention of skin aging.

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“…However, the obtained results with the assayed extract were not as promising as initially intended, which was not expected as sugarcane-derived polyphenols (e.g. caffeic acid, ellagic acid, gallic acid) are reported to induce collagen synthesis [24,109,110]. Perhaps, the tested concentration was not enough to positively induce the production of collagen.…”

Section: Cytokeratin 14 and Collagen I α1 Productionmentioning

confidence: 73%

“…The processing of sugarcane generates annually a great number of by-products such as bagasse and straw, which are the main resultant wastes [24][25][26][27]. Sugarcane straw is rich in polysaccharides and other compounds, being composed of 33-45% cellulose, 18-30% hemicellulose, 17-41% lignin, 1-12% ashes, and 5-7% extractives [24,28]. Furthermore, sugarcane is also a source of phenolic compounds which exhibit several properties, such as anti-allergenic, anti-atherogenic, anti-in ammatory, antimicrobial, and antioxidant activities [24,29,30].…”

Section: Introductionmentioning

confidence: 99%

Skincare Potential of a Sustainable Postbiotic Extract Produced Through Sugarcane Straw Fermentation by Saccharomyces Cerevisiae

Duarte

Carvalho

et al. 2023

Preprint

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Postbiotics, a new class of molecules derived from microorganism’s metabolism, are defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. They can be produced by fermentation, using culture media with glucose as the carbon source, and lactic acid bacteria of the genus Lactobacillus, and/or yeast, mainly Saccharomyces cerevisiae as fermentative microorganisms. Postbiotics comprise different metabolites, and have important biological properties (antioxidant, anti-inflammatory, etc), which is why their use in cosmetics should be considered. During this work, the production of postbiotics was carried out by fermentation with sugarcane straw, as a source of carbon and other active compounds, and as a more sustainable and promising process to obtain more bioactive extracts at the end. For this, its saccharification process was carried out with cellulase at 55 ºC for 24 h. Fermentation was performed sequentially after saccharification at 30 ºC, for 72h, using S. cerevisiae. The cells-free extract was characterized regarding its composition, antioxidant activity, and skincare potential. Its use was safe at concentrations below ~ 20 mg.mL− 1 for keratinocytes and ~ 7.5 mg.mL− 1 for fibroblasts. It showed antioxidant activity, with ABTS IC50 of 1.88 mg.mL− 1, and inhibited elastase and tyrosinase activities by 83.4% and 42.4%, respectively, at the maximum concentration tested (20 mg.mL− 1). In addition, it promoted the production of cytokeratin 14, and demonstrated anti-inflammatory activity at a concentration of 10 mg.mL− 1. Finally, in the skin microbiota of human volunteers, the extract inhibited the Cutibacterium acnes bacterium and the Malassezia fungal genus. In short, postbiotics were successfully produced using straw as substrate, and as source of carbon and phenolic compounds. These postbiotics showed bioactive properties that potentiate their use in the development of cosmetic and skincare products, such as the treatment of acne or other skin diseases, due to their anti-inflammatory and inhibitory effect on the bacteria responsible for acne, as well as on potentially colonizing fungi.

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Potential of sugarcane extracts as cosmetic and skincare ingredients

Cited by 30 publications

References 97 publications

Sugarcane Straw Polyphenols as Potential Food and Nutraceutical Ingredient

Sugarcane Straw Polyphenols as Potential Food and Nutraceutical Ingredient

Ethanolic Fenugreek Extract: Its Molecular Mechanisms against Skin Aging and the Enhanced Functions by Nanoencapsulation

Skincare Potential of a Sustainable Postbiotic Extract Produced Through Sugarcane Straw Fermentation by Saccharomyces Cerevisiae

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