Posttraumatic occurrence of infantile digital fibromatosis. A histologic and electron microscopic study

Miyamoto, T.

doi:10.1001/archderm.122.8.915

Cited by 8 publications

(4 citation statements)

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“…Infantile digital fibroma is a distinctive myofibroblastic tumor that contains characteristic round eosinophilic cytoplasmic inclusions [3,170,171]. It occurs predominantly on the digits of infants and young children, although histologically identical lesions can arise in extradigital locations, such as the arm, leg, and breast, and in older children and adults [172–178]. This has resulted in the alternative designation of “inclusion-bearing fibromatosis.” The small dome-shaped papule or nodule is covered by smooth skin (Fig.…”

Section: Fibromatosesmentioning

confidence: 99%

Fibroblastic and Myofibroblastic Tumors in Children and Adolescents

2012

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Fibroblastic and myofibroblastic tumors in children and adolescents are a relatively common group of soft tissue proliferations that range from reactive to hamartomatous to neoplastic, with a full spectrum of benign, intermediate, and malignant neoplasms. These lesions are diagnostically challenging because of morphologic and immunohistochemical overlap, despite significant clinical, genetic, and prognostic differences. The fibromatoses are a major subgroup, and all types of fibromatoses can occur in the 1st 2 decades of life. Intermediate and malignant fibroblastic-myofibroblastic tumors are an important group that includes variants of fibrosarcoma and other tumors with recurrent cytogenetic or molecular genetic abnormalities and low metastatic potential. Pathologic examination is enhanced by adjunct techniques, such as immunohistochemistry, cytogenetics, and molecular genetics, although morphology provides the ultimate criteria for a specific diagnosis. This article reviews the clinicopathologic features of fibroblastic and myofibroblastic tumors with an emphasis on the unique aspects of these neoplasms in children and adolescents, the use of diagnostic adjuncts, and differential diagnoses.

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Section: Fibromatosesmentioning

confidence: 99%

Fibroblastic and Myofibroblastic Tumors in Children and Adolescents

2012

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“…Supporting this hypothesis, Henderson et al found that the inclusion bodies of IDF stain with an anti‐calponin 1 antibody; calponin 1 may be involved with regulating actin and myosin interactions during smooth muscle cell contraction. Some IDF lesions have arisen after trauma, indicating that trauma may play a role in the development of this lesion .…”

Section: Discussionmentioning

confidence: 99%

Recurrence of Two Nodules on the Toe of a 10‐Year‐Old Boy

Gillooly

Berry

Elwood

et al. 2016

Pediatric Dermatology

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“…En algunos casos se ha descrito un antecedente traumático previo al desarrollo de las lesiones [4]. Las lesiones son asintomáticas, pero en los casos de lesiones múltiples pueden dificultar la movilidad articular o causar deformidades digitales.…”

Section: Discussionunclassified