Poststroke Seizures

Abstract

Stroke is the most common cause of seizures in the elderly, and seizures are among the most common neurologic sequelae of stroke. About 10% of all stroke patients experience seizures, from stroke onset until several years later. This review discusses current understanding of the epidemiology, pathogenesis, classification, clinical manifestations, diagnostic studies, differential diagnosis, and management issues of seizures associated with various cerebrovascular lesions, with a focus on anticonvulsant use in the elderly.

Seizure development after stroke

“…This study revealed that recurrent seizures were associated with late seizures, and recurrence ratio was higher in late seizures (89.4%). This is consistent with some previous studies (11,19,30,32–34,36,37). In some other series, although, the risk of recurrent seizures was higher with early seizures (1,2,17).…”

Seizure development after stroke

“…This study revealed that recurrent seizures were associated with late seizures, and recurrence ratio was higher in late seizures (89.4%). This is consistent with some previous studies (11,19,30,32–34,36,37). In some other series, although, the risk of recurrent seizures was higher with early seizures (1,2,17).…”

Predictors of Pharmaco-Resistance in Patients with Post-Stroke Epilepsy

“…Importantly, not all epileptic patients carry the same risk to be refractory to ASMs, and etiology can play a role. Despite differences in study cohorts, definitions, and follow-up times, the rate of treatment refractoriness we found is consistent with the figures reported in prior studies and suggests that, although PSE has overall a good prognosis and patients are generally responsive to pharmacological treatment, a not negligible percentage of cases become drug resistant [10][11][12][13][14].…”

Childhood strokes in China describing clinical characteristics, risk factors and performance indicators: a case-series study

“…The most common presenting symptom among patients who had an AIS was acute focal neurological deficit, which was consistent with the literature reports 6. Seizures occurred in 17.16% cases, which was consistent with Silverman and Zelano’s7 8 reports that poststroke seizures occurred in 5%–20%, but lower than Polat et al ’s9 report (59% patients).…”

Seizure development after stroke

“…This study revealed that recurrent seizures were associated with late seizures, and recurrence ratio was higher in late seizures (89.4%). This is consistent with some previous studies (11,19,30,32–34,36,37). In some other series, although, the risk of recurrent seizures was higher with early seizures (1,2,17).…”

Predictors of Pharmaco-Resistance in Patients with Post-Stroke Epilepsy

“…Importantly, not all epileptic patients carry the same risk to be refractory to ASMs, and etiology can play a role. Despite differences in study cohorts, definitions, and follow-up times, the rate of treatment refractoriness we found is consistent with the figures reported in prior studies and suggests that, although PSE has overall a good prognosis and patients are generally responsive to pharmacological treatment, a not negligible percentage of cases become drug resistant [10][11][12][13][14].…”

Childhood strokes in China describing clinical characteristics, risk factors and performance indicators: a case-series study

“…The most common presenting symptom among patients who had an AIS was acute focal neurological deficit, which was consistent with the literature reports 6. Seizures occurred in 17.16% cases, which was consistent with Silverman and Zelano’s7 8 reports that poststroke seizures occurred in 5%–20%, but lower than Polat et al ’s9 report (59% patients).…”

Seizure development after stroke

“…This study revealed that recurrent seizures were associated with late seizures, and recurrence ratio was higher in late seizures (89.4%). This is consistent with some previous studies (11,19,30,32–34,36,37). In some other series, although, the risk of recurrent seizures was higher with early seizures (1,2,17).…”

Predictors of Pharmaco-Resistance in Patients with Post-Stroke Epilepsy

“…Importantly, not all epileptic patients carry the same risk to be refractory to ASMs, and etiology can play a role. Despite differences in study cohorts, definitions, and follow-up times, the rate of treatment refractoriness we found is consistent with the figures reported in prior studies and suggests that, although PSE has overall a good prognosis and patients are generally responsive to pharmacological treatment, a not negligible percentage of cases become drug resistant [10][11][12][13][14].…”

Childhood strokes in China describing clinical characteristics, risk factors and performance indicators: a case-series study

“…The most common presenting symptom among patients who had an AIS was acute focal neurological deficit, which was consistent with the literature reports 6. Seizures occurred in 17.16% cases, which was consistent with Silverman and Zelano’s7 8 reports that poststroke seizures occurred in 5%–20%, but lower than Polat et al ’s9 report (59% patients).…”