Postpancreatectomy hemorrhage (PPH)–An International Study Group of Pancreatic Surgery (ISGPS) definition

Wente, Moritz N.; Veit, J.; Bassi, Claudio; Dervenis, Christos; Fingerhut, Abe; Gouma, Dirk J.; Izbicki, Jakob R.; Neoptolemos, John P.; Padbury, Robert; Sarr, Michael G.; Yeo, Charles J.; Büchler, Markus W.

doi:10.1016/j.surg.2007.02.001

Cited by 2,047 publications

(1,452 citation statements)

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“…Definitions of pancreatic fistula, delayed gastric emptying and postoperative bleeding were based on the International Study Group of Pancreatic Surgery (13)(14)(15). The onset of postoperative pancreatogenic diabetes (type IIIc) was based on the criteria of the American Diabetes Association (16).…”

Section: Methodsmentioning

confidence: 99%

A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors

et al. 2016

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Background: Pancreatic neuroendocrine tumors (pNETs) comprise a heterogeneous group of tumors with a varied biological behavior. In the present study, we analyzed the experience of 79 pNETs resected between 1993 and 2015. The pathologic prognostic factors (European Neuroendocrine Tumor Society, ENETS; and AJCC) classification, vascular invasion (VI), proliferation index (ki-67) and the presence of necrosis were retrospectively reviewed.Methods: The clinical data of 79 patients with pNETs who underwent surgery were retrospectively analyzed. Mortality rates and Kaplan-Meier estimates were used to evaluate survival over time for pathologic stages, tumor functionality, and vascular invasion. Cox proportional hazards models were used to calculate the hazard ratio regarding ENETS, AJCC staging, sex, tumor functionality and vascular invasion.Results: The male:female ratio was 40:39. Twenty-one patients (26%) had functional tumors and 58 (73.4%) had nonfunctional tumors, of which 35 (44.3%) were diagnosed incidentally. Seventeen Whipple procedures, 46 distal pancreatectomies (including 26 laparoscopic and 20 open procedures), 8 laparoscopic central pancreatectomies, 1 laparoscopic resection of the uncinated process and 7 enucleations (one laparoscopic) were performed. Vascular invasion and necrosis were observed in 29 of 75 cases (38.6%) and in 16 cases (29%), respectively. The comparison between survivor functions of ENETS staging categories showed statistically significant differences (p = 0.042). Mortality rate was higher in patients with non-functioning tumors compared with hormonally functioning tumors (p = 0.052) and in those with vascular invasion (p = 0.186).Conclusions: In spite of the heterogeneity of pNETs, the ENETS TNM classification efficiently predicts long-term prognosis. The non-functioning tumors and the presence of vascular invasion are associated with poor prognosis.

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Section: Methodsmentioning

confidence: 99%

A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors

et al. 2016

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“…For the diagnosis of pancreatic fistula, we used the criteria of the International Study Group on the Definition of Pancreatic Fistula (GIEDFP) 5 , and for the diagnosis of bleeding and delayed postoperative gastric emptying, the criteria of the International Study Group of Pancreatic surgery (GIECP) 6,7 .…”

Section: Methods Methods Methods Methodsmentioning

confidence: 99%

Fifty consecutive pancreatectomies without mortality

Amico

Barreto

Alves

et al. 2016

Rev. Col. Bras. Cir.

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ABSTRACT ABSTRACT ABSTRACTObjective: Objective: Objective: Objective: Objective: to report the group's experience with a series of patients undergoing pancreatic resection presenting null mortality rates. Methods:Methods: Methods: Methods: Methods: we prospectively studied 50 consecutive patients undergoing pancreatic resections for periampullary or pancreatic diseases. Main local complications were defined according to international criteria. In-hospital mortality was defined as death occurring in the first 90 postoperative days. Results:Results: Results: Results: Results: patients' age ranged between 16 and 90 years (average: 53.3). We found anemia (Hb < 12g/dl) and preoperative jaundice in 38% and 40% of cases, respectively. Most patients presented with peri-ampullary tumors (66%). The most common surgical procedure was the Kausch-----Whipple operation (70%). Six patients (12%) needed to undergo resection of a segment of the mesenteric-portal axis. The mean operative time was 445.1 minutes. Twenty two patients (44%) showed no clinical complications and presented mean hospital stay of 10.3 days. The most frequent complications were pancreatic fistula (56%), delayed gastric emptying (17.1%) and bleeding (16%). Conclusion Conclusion Conclusion Conclusion Conclusion: within the last three decades, pancreatic resection is still considered a challenge, especially outside large specialized centers. Nevertheless, even in our country (Brazil), teams seasoned in such procedure can reach low mortality rates.

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“…LoS was calculated from operation day to discharge date. Pancreatic fistulas and postoperative hemorrhages were defined using the International Study Group of Pancreatic Surgery (ISGPS) criteria [14,15].…”

Section: Perioperative Outcomesmentioning

confidence: 99%

Short-term outcomes after distal pancreatectomy: Laparotomy vs. laparoscopy – A single-center series

et al. 2016

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h i g h l i g h t sLaparoscopy has been recently used more frequently for distal pancreatectomy. Postoperative complications and oncologic outcomes were similar in this study. Length of stay was shorter for the patients operated by laparoscopy. Laparoscopy should be offered when technically feasible. a r t i c l e i n f o Conclusion: Short-term outcomes after open and laparoscopic distal pancreatectomy regarding postoperative complications and mortality were similar, but length of stay was significantly shorter for the laparoscopic approach. Hence, laparoscopic distal pancreatectomy should be offered to all suitable patients.

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Postpancreatectomy hemorrhage (PPH)–An International Study Group of Pancreatic Surgery (ISGPS) definition

Cited by 2,047 publications

References 34 publications

A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors

A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors

Fifty consecutive pancreatectomies without mortality

Short-term outcomes after distal pancreatectomy: Laparotomy vs. laparoscopy – A single-center series

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Postpancreatectomy hemorrhage (PPH)–An International Study Group of Pancreatic Surgery (ISGPS) definition

Cited by 2,047 publications

References 34 publications

A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors

A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors

Fifty consecutive pancreatectomies without mortality

Short-term outcomes after distal pancreatectomy: Laparotomy vs. laparoscopy – A single-center series

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A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors

A single institutions 21-year experience with surgically resected pancreatic neuroendocrine tumors: an analysis of survival and prognostic factors