Postimplantation Syndrome after Endovascular Aortic Repair Using the Anaconda™ Endograft

Nano, Giovanni; Occhiuto, Maria Teresa; Stegher, Silvia; Malacrida, Giovanni; Cova, Marta; Righini, Paolo; Tealdi, D.G.; Mazzaccaro, Daniela

doi:10.1016/j.avsg.2014.03.001

Cited by 24 publications

(32 citation statements)

References 13 publications

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“…Finally, yet importantly, a significant difference in the incidence of postimplantation syndrome was recorded after the use of the Incraft endograft compared with the Ovation graft, which could be due to the manufacture of nitinol stents of the former, as it has been reported with the use of other endografts (15). This occurrence did not affect neither postoperative course nor in-hospital stay, which was similar for both groups, but it should be kept in mind and especially stressed to the patient, who must be informed on the possibility of this complication after the Incraft implantation.…”

Section: Discussionmentioning

confidence: 85%

Preliminary experience with the use of ultra-low profile endografts

Mazzaccaro

Malacrida

Amato

et al. 2017

Diagn Interv Radiol

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Section: Discussionmentioning

confidence: 85%

Preliminary experience with the use of ultra-low profile endografts

Mazzaccaro

Malacrida

Amato

et al. 2017

Diagn Interv Radiol

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“…In any case, PIS related to Anaconda® endografts had the highest incidence in published literature, except in one study by Nano et al [8] in which the reported incidence was of only 20.3% [4,18,25]. In that study, however, isolated fever without any sign of infection and maintained for more than a week occurred in many patients, even after administration of corticosteroids (median duration, 11 days, (4-30 days)).…”

Section: Endograft Materialsmentioning

confidence: 84%

“…In another study, with a retrospective design, of 118 patients who underwent EVAR but only with Anaconda endograft. These authors used the same definition of PIS with leukocytes >12.000/μl and temperature and reported an incidence of PIS of 20.3% (24 patients) [8]. Another retrospective study with 87 patients, using the same definition for PIS, found an incidence of 39%.…”

Section: Definition and Incidencementioning

confidence: 98%

“…There are several proposed combinations of fever, leukocytosis, and elevated C-reactive protein (CRP) used as definition for PIS in the literature. Some authors defined PIS as the presence of fever coinciding with an elevated serum CRP level, whereas the majority of them adapted the systemic inflammatory response syndrome (SIRS) criteria and defined PIS as the presence of fever combined with leukocytosis [1,2,[4][5][6][7][8][9][10][11].…”

Section: Definition and Incidencementioning

confidence: 99%

“…The majority of the studies pointed to a higher incidence of PIS or a greater increase of inflammatory markers in polyester-based endografts [4,5,8,18,20]. Voûte et al [5] constructed a multivariable risk model for PIS, and woven polyester constitution of the endograft was the only significant factor associated with an increased risk of developing PIS (HR 5.58; p = 0.007).…”

Section: Endograft Materialsmentioning

confidence: 99%

See 2 more Smart Citations

Postimplantation Syndrome after Endovascular Aneurysm Repair

Ferreira¹,

Gonçalves²

2019

Abdominal Aortic Aneurysm - From Basic Research to Clinical Practice

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Endovascular aneurysm repair is associated, in a significant proportion of patients, to a systemic inflammatory response denominated postimplantation syndrome (PIS). PIS is characterized by fatigue, fever, and a rise in inflammatory biomarkers after the operation. However, the exact definition is still a matter of debate. There are several proposed definitions for PIS in the literature resulting in significant variability of PIS incidence (ranging from 2% to 100%). The etiology of PIS is not entirely clear. Endograft composition, aortic thrombus, intestinal bacterial translocation, and contrast media may contribute to PIS but the first seems to be the most important determinant. This clinical entity may have clinical consequences in length of hospital stay, readmissions, renal function, cardiovascular events, endoleak rate, and quality of life, but current data are insufficient for definitive conclusions. Despite of absence of stablished treatment for PIS, non-steroid and steroid anti-inflammatory drugs are currently advocated when clinical suspicion arises. Prevention may be achieved with perioperative administration of a steroid drug. Since it may have adverse effects, further knowledge of the real incidence of PIS and its clinical consequences is imperative.

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Efficiently Simulating an Endograft Deployment: A Methodology for Detailed CFD Analyses

et al. 2020

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Numerical models of endografts for the simulation of endovascular aneurysm repair are increasingly important in the improvement of device designs and patient outcomes. Nevertheless, current finite element analysis (FEA) models of complete endograft devices come at a high computational cost, requiring days of runtime, therefore restricting their applicability. In the current study, an efficient FEA model of the Anaconda™ endograft (Terumo Aortic, UK) was developed, able to yield results in just over 4 h, an order of magnitude less than similar models found in the literature. The model was used to replicate a physical device that was deployed in a 3D printed aorta and comparison of the two shapes illustrated a less than 5 mm placement error of the model in the regions of interest, consistent with other more computationally intensive models in the literature. Furthermore, the final goal of the study was to utilize the deployed fabric model in a hemodynamic analysis that would incorporate realistic fabric folds, a feature that is almost always omitted in similar simulations. By successfully exporting the deployed graft geometry into a flow analysis, it was illustrated that the inclusion of fabric wrinkles enabled clinically significant flow patterns such as flow stagnation and recirculation to be detected, paving the way for this modelling methodology to be used in future for stent design optimisation.

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Postimplantation Syndrome after Endovascular Aortic Repair Using the Anaconda™ Endograft

Cited by 24 publications

References 13 publications

Preliminary experience with the use of ultra-low profile endografts

Preliminary experience with the use of ultra-low profile endografts

Postimplantation Syndrome after Endovascular Aneurysm Repair

Efficiently Simulating an Endograft Deployment: A Methodology for Detailed CFD Analyses

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