Posterior Capsule Opacification

Bendazac Lysine Inhibition of Human Lens Epithelial Cell Adhesion to Polymethylmethacrylate Intraocular Lenses

“…Lens epithelial cells (LECs) remaining after extracapsular cataract extraction and IOL implantation are considered the key effectors in PCO development [8]. Activation of LECs, resulting in their proliferation and migra-tion onto the posterior capsule behind the implanted IOL, might be due to the surgical trauma, which causes a breakdown of the blood aqueous barrier and evokes an inflammatory-type response [9,10].…”

Bendazac Lysine Inhibition of Human Lens Epithelial Cell Adhesion to Polymethylmethacrylate Intraocular Lenses

“…Lens epithelial cells (LECs) remaining after extracapsular cataract extraction and IOL implantation are considered the key effectors in PCO development [8]. Activation of LECs, resulting in their proliferation and migra-tion onto the posterior capsule behind the implanted IOL, might be due to the surgical trauma, which causes a breakdown of the blood aqueous barrier and evokes an inflammatory-type response [9,10].…”

Prevention of posterior capsule opacification by retinoic acid and mitomycin

“…The proliferation and migration of residual lens epithelial cells (LECs) cause this condition [5,7,8,16,20,21,24,33]. The incidence of PCO 3-5 years after surgery is 8-50% in adults [22,23,30,34] but 95% in children [14,17].…”

Equator ring efficacy in maintaining capsular bag integrity and transparency after cataract removal in monkey eyes

“…The mechanism of posterior capsule opacification and wrinkling following cataract extraction in humans has been explained by specular-microscopic [8], light-microscopic, and ultrastructural studies [7,9]. Posterior capsular opacification is a manifestation of the migration of lens epithelial cells onto the posterior capsule.…”

Bendazac Lysine Inhibition of Human Lens Epithelial Cell Adhesion to Polymethylmethacrylate Intraocular Lenses

“…Lens epithelial cells (LECs) remaining after extracapsular cataract extraction and IOL implantation are considered the key effectors in PCO development [8]. Activation of LECs, resulting in their proliferation and migra-tion onto the posterior capsule behind the implanted IOL, might be due to the surgical trauma, which causes a breakdown of the blood aqueous barrier and evokes an inflammatory-type response [9,10].…”

Prevention of posterior capsule opacification by retinoic acid and mitomycin

“…The proliferation and migration of residual lens epithelial cells (LECs) cause this condition [5,7,8,16,20,21,24,33]. The incidence of PCO 3-5 years after surgery is 8-50% in adults [22,23,30,34] but 95% in children [14,17].…”

Equator ring efficacy in maintaining capsular bag integrity and transparency after cataract removal in monkey eyes

“…The mechanism of posterior capsule opacification and wrinkling following cataract extraction in humans has been explained by specular-microscopic [8], light-microscopic, and ultrastructural studies [7,9]. Posterior capsular opacification is a manifestation of the migration of lens epithelial cells onto the posterior capsule.…”

Bendazac Lysine Inhibition of Human Lens Epithelial Cell Adhesion to Polymethylmethacrylate Intraocular Lenses

“…Lens epithelial cells (LECs) remaining after extracapsular cataract extraction and IOL implantation are considered the key effectors in PCO development [8]. Activation of LECs, resulting in their proliferation and migra-tion onto the posterior capsule behind the implanted IOL, might be due to the surgical trauma, which causes a breakdown of the blood aqueous barrier and evokes an inflammatory-type response [9,10].…”

Prevention of posterior capsule opacification by retinoic acid and mitomycin

“…The proliferation and migration of residual lens epithelial cells (LECs) cause this condition [5,7,8,16,20,21,24,33]. The incidence of PCO 3-5 years after surgery is 8-50% in adults [22,23,30,34] but 95% in children [14,17].…”

Equator ring efficacy in maintaining capsular bag integrity and transparency after cataract removal in monkey eyes

“…The mechanism of posterior capsule opacification and wrinkling following cataract extraction in humans has been explained by specular-microscopic [8], light-microscopic, and ultrastructural studies [7,9]. Posterior capsular opacification is a manifestation of the migration of lens epithelial cells onto the posterior capsule.…”