Post-COVID Erectile Dysfunction: The Exercise May Be a Good Considered Complementary Choice

Is There an Effect of Lifestyle Changes on Psoriasis-Associated Erectile Dysfunction?

“…Although there are no published studies to clarify the effect of lifestyle changes (exercise and diet intervention) on ED in psoriasis patients, the above-mentioned mechanism explaining the improvement of PP after dietary and exercise intervention is very similar to the explanation of the improvement in ED after adhering to lifestyle-modification programs (Ismail, 2022a(Ismail, , 2022bIsmail & Abdelghany, 2022).…”

Post-COVID changes of semen parameters: a new era for physical activity that needs investigation

“…Lifestyle changes (increasing physical activity) have been suggested as adjunctive treatment modalities to address some post-COVID complications that manifest in the male genital systems, such as erectile dysfunction [12][13][14][15] which is defined as inability to maintain or attain penile erection sufficient for sexual intercourse [16,17], but up until this point, no medical trends have been focused on utilizing the advantages of exercise to improve post-COVID related changes in semen parameters.…”

“…COVID is associated with low semen quality due to the low production of antioxidative enzymes [13,14]. The induction of antioxidant enzymes via moderate-intensity exercise seems to be related to the activation of spermatogenesis-related factors such as nuclear factor kappa B and mitogen-activated protein kinase [23].…”

“…COVID is associated with high inflammatory markers and cytokines within different body parts / systems including testes [13,14]…”

“…Additionally, exercise may strengthen the immune system, which is typically impaired in post-COVID men with reproductive / genital system issues. The following are some of the hypothesized mechanisms by which exercise may boost immunity in different body parts including the reproductive / genital system: (a) increasing T-lymphocytes, neutrophils, macrophages, and monocytes, which are essential components of the body's defense system against infectious diseases; (b) increasing immunoglobulin levels; and (c) preventing the rise of high circulating levels of C-reactive protein and pro-inflammatory markers [13,14]. Correction of systemic inflammatory milieu may be associated with improvement in the localized testicular inflammation, hence sperm production and quality may improve.…”