Possible Strategies to Reduce the Tumorigenic Risk of Reprogrammed Normal and Cancer Cells
Ying-Chu Lin,
Cha-Chien Ku,
Kenly Wuputra
et al.
Abstract:The reprogramming of somatic cells to pluripotent stem cells has immense potential for use in regenerating or redeveloping tissues for transplantation, and the future application of this method is one of the most important research topics in regenerative medicine. These cells are generated from normal cells, adult stem cells, or neoplastic cancer cells. They express embryonic stem cell markers, such as OCT4, SOX2, and NANOG, and can differentiate into all tissue types in adults, both in vitro and in vivo. Howe… Show more
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