Possible mode of action of antiherpetic activities of a proteoglycan isolated from the mycelia of Ganoderma lucidum in vitro

The optimization of sulfation modification conditions for ophiopogonpolysaccharide based on antiviral activity

“…The DS of sOPS 3 was lower than those of sOPS 2 , sOPS 5 and sOPS 1 , while its virus inhibition rate was the highest. It suggests that antiviral activity of sulfated polysaccharides depend on suitable DS [38,39]. Too high DS maybe increase the cytotoxicity of sulfated polysaccharides resulting in cell death.…”

The inhibitory effect on aldose reductase by an extract of Ganoderma lucidum

“…Furthermore, this dark mushroom with a glossy exterior and a woody texture has long been reputed to increase youth, vigor and vitality. The specific reported attributes of G. lucidum include being cytotoxic (Toth et al, 1982), antimicrobial (Yoon et al, 1994), anti-HIV (El-Mekkawy et al, 1998), antiinflammatory (Giner-Larza et al, 2000), antitumor, anticancer (Müller et al, 2006), antifungal (Wang and Ng, 2006) and antiherpetic (Liu et al, 2004). It is also reported to be a 5α-reductase inhibitor ; however, the aldose reductase inhibitory activity of G. lucidum has never been reported.…”

Antiviral activity and constituent of Ardisia chinensis benth against coxsackie B3 virus

“…The present study showed that Ardisia chinensis possesses antiviral activity against Cox B3, and its antiviral activity is mainly attributed to its polysaccharide constituent. Natural polysaccharides from plants, algae and fungi are known to possess potent antiviral activities (Eo et al, 1999;Xu et al, 1999;Liu et al, 2004;Chiu et al, 2004). In particular, sulfated polysaccharides attract more attention due to their significant antiviral effects (Ghosh et al, 2004;Zhu et al, 2004).…”