2006
DOI: 10.1590/s1516-31802006000400010
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Abstract: There is a positive correlation between serum and peritoneal fluid values of CA-125 in women with and without endometriosis, and their levels are higher in peritoneal fluid. Advanced endometriosis is related to higher levels in both serum and peritoneal fluid.

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Cited by 41 publications
(46 citation statements)
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“…There are publications reporting a positive correlation between serum and peritoneal fluid values of CA-125 in women with and without endo metriosis [21] but we did not find such a correlation in our study. Cancer antigen 125 levels are much higher in peritoneal fluid but to compare results between studies we should have information about the manufacturer of the CA-125 test and the way of preparing the test (e.g.…”
Section: Discussioncontrasting
confidence: 99%
“…There are publications reporting a positive correlation between serum and peritoneal fluid values of CA-125 in women with and without endo metriosis [21] but we did not find such a correlation in our study. Cancer antigen 125 levels are much higher in peritoneal fluid but to compare results between studies we should have information about the manufacturer of the CA-125 test and the way of preparing the test (e.g.…”
Section: Discussioncontrasting
confidence: 99%
“…The present study findings not only confirm increased PF concentrations of the ovarian cancer marker CA125 in patients with endometriosis (24,25), but also demonstrate for the first time, to the best of our knowledge, similarly increased levels of the novel marker HE4 in this compartment. The two markers are shown to be closely correlated (P<0.01; Fig.…”
Section: Discussionsupporting
confidence: 85%
“…Serum CA125 has also been demonstrated to be increased in non-malignant disorders (29). The correlation between serum and PF CA125 has been previously demonstrated (25). Human epididymis protein 4 (HE4), a small glycoprotein and protease inhibitor first identified in epididymal epithelium, has been identified as an ovarian cancer marker, particularly for the serous and endometrioid type (30), and is superior to CA125 (31) either on its own or in combination with CA125 as defined by a higher detection rate (32)(33)(34).…”
Section: Introductionmentioning
confidence: 76%
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“…Likewise, combining laboratory tests such as CA125 level determinations with imaging methods such as ultrasonography, tomography and magnetic resonance provides relative value for reaching a conclusive diagnosis in the initial stages of endometriosis. [12][13][14] Combining laparoscopy with histopathological examination yields greater sensitivity for the definitive diagnosis of the disease and also decreases the diagnostic errors. 15 Among the 976 laparoscopies performed in this study, the frequency of endometriosis was 35.3%.…”
Section: Discussionmentioning
confidence: 99%