Portable immunosensor directly and rapidly detects Mycobacterium tuberculosis in sputum

Abstract

Tuberculosis (TB) remains a public health problem that cannot be ignored. The portable and efficient detection of Mycobacterium tuberculosis (MTB) is important for the effective control of this disease. However,...

A self-contained and integrated microfluidic nano-detection system for the biosensing and analysis of molecular interactions

“…These findings show that the prepared sensor can detect the MTB Ag85B protein secreted by MTB. Compared to a hospital's conventional detection methods (incubation using BACTEC MGIT 960, 32 ELISA, 33 PCR 34 and sensor 35 ), our device can complete the detection at an early stage, in a shorter time, and can be successfully applied in an outdoor environment.…”

Rapid detection of airborne protein from Mycobacterium tuberculosis using a biosensor detection system

“…Compared with other molecular, immune and sensor detection technologies, our biosensor can detect MTB Ag85B protein with a wider concentration range in a shorter time. 20 However, the sample usually requires manual labor to load it onto the actual sensor for detection, which will cause errors. 15 Moreover, since MTB is mostly transmitted through air, it is not enough to detect only liquid TB samples.…”