Porous biocompatible implants and tissue scaffolds synthesized by selective laser sintering from Ti and NiTi

Shishkovsky, Igor; Волова, Л. Т.; Кузнецов, М. В.; Morozov, Yu. G.; Parkin, Ivan P.

doi:10.1039/b715313a

Cited by 111 publications

(88 citation statements)

References 34 publications

(47 reference statements)

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“…[2,4,6,10,17,[25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40] Functional polymer coatings, including biofilms and plasma polymers, have attracted increasing interest in the recent past. [10,32,39,[41][42][43][44][45][46] This is because the polymer composition can be adapted for a special requirement like antibacterial activity.…”

Section: Introductionmentioning

confidence: 99%

Surface Modification of Nickel/Titanium Alloy and Titanium Surfaces via a Polyelectrolyte Multilayer/Calcium Phosphate Hybrid Coating

Schweizer¹,

Schuster²,

Junginger³

et al. 2010

Macro Materials & Eng

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The report shows that simple LbL deposition of positively charged chitosan and negatively charged heparin can be used to efficiently modify the native surface of both NiTi and Ti without any previous treatments. Moreover, mineralization of the polymer multilayers with calcium phosphate leads to surfaces with low contact angles around 70 and 20° for NiTi and Ti, respectively. This suggests that a polymer multilayer/calcium phosphate hybrid coating could be useful for making NiTi or Ti implants that are at the same time antibacterial (via the chitosan), suppress blood clot formation (via the heparin), and favor fast endothelialization (via the improved surface hydrophilicity compared to the respective neat material). magnified image

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Section: Introductionmentioning

confidence: 99%

Surface Modification of Nickel/Titanium Alloy and Titanium Surfaces via a Polyelectrolyte Multilayer/Calcium Phosphate Hybrid Coating

Schweizer¹,

Schuster²,

Junginger³

et al. 2010

Macro Materials & Eng

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“…This device, known as the realizer, provides cobalt-chromium and gold-based alloy structures with approximately 30 μm layer thicknesses. In another study, Shishkovsky et al described the use of selective laser sintering/melting to fabricate implants for craniofacial applications out of Nitinol, a superelastic/shape-memory material, or titanium [59]. A Nitinol structure with a tooth-like shape and porous morphology was demonstrated using this approach.…”

Section: Laser-based Prototyping Methodsmentioning

confidence: 99%

Laser Engineering of Surface Structures

Narayan

Goering

Balani³

et al. 2014

Biosurfaces

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Over the past half century, rapid progress has been made in laser-based medical diagnosis and treatment, as well as in laser-based medical device fabrication. Lasers have unique capabilities for coating, machining, melting, polymerizing, sintering, and welding materials that are used in implantable and transdermal medical devices. In this review, academic and industrial developments involving laser processing of materials for dental, orthopedic, neural, ophthalmic, cardiovascular and transdermal applications are described. In addition, laser processing of nanoscale materials for medical applications is discussed. Finally, the challenges associated with commercialization of laser biomaterials are considered. Due to the unique capabilities provided by laser-based processes, it is anticipated that the use of laser biomaterials in implantable and transdermal medical devices will markedly increase over the coming years.

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“…They may outperform CO 2 lasers for sintering metallic and ceramic materials, which absorb much better at short wavelengths [46]. Consequently, pure titanium, Ti-6Al-4V and NiTi shape memory alloy, which are known for their biocompatibility and good corrosion resistance, have been successfully sintered into 3D porous structures for medical implantation using Nd:YAG laser [47,48]. Bioceramics such as hydroxyapatite (HA) could also be sintered to form customized implants for bone substitution [49].…”

Section: Materials For Slsmentioning

confidence: 99%

Selective Laser Sintering and Its Biomedical Applications

Duan

Wang

2013

Laser Technology in Biomimetics

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Selective laser sintering (SLS), a mature and versatile rapid prototyping (RP) technology, uses a laser beam to selectively sinter powdered materials to form three-dimensional objects, porous or non-porous, according to the computer-aided design which can be based on data obtained from advanced medical imaging technologies such as magnetic resonance imaging (MRI) and computer tomography (CT). In this chapter, major RP technologies suitable for biomedical applications are briefly introduced first. A review is made on SLS, including its working principle, modification of commercial SLS machines for fabricating biomedical products, biomedical SLS materials, and optimization of SLS parameters. Finally, a detailed presentation is given on the biomedical application of SLS, focusing on the fabrication of tissue engineering scaffolds and drug or biomolecule delivery vehicles. It is shown that SLS has great potential for many biomimetic and biomedical applications.

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Porous biocompatible implants and tissue scaffolds synthesized by selective laser sintering from Ti and NiTi

Cited by 111 publications

References 34 publications

Surface Modification of Nickel/Titanium Alloy and Titanium Surfaces via a Polyelectrolyte Multilayer/Calcium Phosphate Hybrid Coating

Surface Modification of Nickel/Titanium Alloy and Titanium Surfaces via a Polyelectrolyte Multilayer/Calcium Phosphate Hybrid Coating

Laser Engineering of Surface Structures

Selective Laser Sintering and Its Biomedical Applications

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