Porokeratotic eccrine ostial and dermal duct nevus: a unique case treated with CO₂ laser

Abstract

Key Clinical MessagePorokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare eccrine hamartoma, with treatment generally being unsatisfactory. The unique features of PEODDN presented include bilateral and facial lesions, and extensive body involvement. Management with CO2 laser was successful, and follow‐up will be necessary to monitor for recurrent lesions.

Widespread presentation and spontaneous regression of porokeratotic eccrine ostial and dermal duct nevus

“…Clinical improvement has been most consistently reported with CO 2 laser. 1 , 4 , 11 , 12 , 13 Improvement has also been reported with topical tretinoin (0.5%) cream with urea (10%) 14 and topical photodynamic therapy with aminolevulinic acid. 15 The 2 infants described here had significant spontaneous improvement in clinical appearance despite widespread involvement noted at birth.…”

Adult-onset porokeratotic eccrine ostial and dermal duct nevus:dermatoscopic findings and treatment with tazarotene

“…Various treatments have Dermatology Online Journal || Photo Vignette been used, but none seems to be regularly effective [6]. Topical corticosteroids (methylprednisolone and clobetasol propionate) can achieve temporary relief [31,32]. Local tretinoin 1% cream, calcipotriene ointment [32], 5-fluorouracil [5], and various keratolytics have been used, including urea ointment or cream [12] and salicylic acid in petrolatum [15], without significant results.…”

Hyperkeratotic papules following Blaschko lines in a 4‐year‐old boy

“…CO2 laser therapy has shown successful results in some cases but is very painful. Because of that, the use in children is difficult . Topical photodynamic therapy (PDT) has also been described as a therapeutic strategy for PEODDN with partial response in some patients …”