Porokeratotic eccrine ostial and dermal duct nevus

Widespread presentation and spontaneous regression of porokeratotic eccrine ostial and dermal duct nevus

“…Other cases have been reported with hemibody 6 , 7 and generalized involvement 8 ; however, this is quite uncommon. Dramatic improvement, as seen in our first 2 cases, has been reported previously in both PEODDN 7 , 9 and PEHFN 10 ( Table I ), however this phenomenon appears to be uncommon with most lesions remaining stable over the patient's life.…”

“…Dramatic improvement, as seen in our first 2 cases, has been reported previously in both PEODDN 7 , 9 and PEHFN 10 ( Table I ), however this phenomenon appears to be uncommon with most lesions remaining stable over the patient's life.…”

“… 15 The 2 infants described here had significant spontaneous improvement in clinical appearance despite widespread involvement noted at birth. This natural regression has been previously reported 8 , 9 , 10 and may be important information for clinicians as well as new parents of children with PEODDN.…”

SkinIndia Quiz 47: Linear pitted plaque over the foot

“…[ 2 ] The lesions are usually asymptomatic but occasionally it may be accompanied by moderate pruritus and anhidrosis. [ 3 4 5 ] The commonly affected sites are palms and soles. Lesions on other parts of the body usually manifest as multiple verrucous, keratotic, brown-to-flesh–colored papules which may coalesce into linear plaques in a Blaschkoid distribution.…”

Porokeratotic Eccrine Nevus May Be Caused by Somatic Connexin26 Mutations

“…Depending on sectioning, these plugs can appear as so-called cornoid lamellae. In addition, hyper(para)keratosis and wavy psoriasiform epidermal acanthosis can also be present (Aloi and Pippione, 1986). Comedo-like or spiky lesions can be prominent in porokeratotic eccrine nevus (PEN) when located on the palms or soles (Sassmannshausen et al , 2000).…”