Porocarcinoma of the left arm: A report of a rare skin cancer case and literature review

Abstract

Porocarcinoma is a rare type of skin cancer that develops from the intraepidermal ductal part of eccrine sweat glands. It can arise de novo or from poroma ground with high potential for locoregional metastatic spread, morbidity, and mortality. It mostly occurs in elderly patients.

Porocarcinoma in a palm reconstructed with a full thickness skin graft: A case report

“…The treatment options for primary tumors without metastasis include wide local excision or Mohs micrographic surgery; the excision margin varies, with 1-2 cm being the most commonly used margin[ 8 , 10 ]. Reconstruction options for defects include primary closure, dermal regeneration templates, skin grafts, flaps, and free tissue transfer[ 6 ].…”

“…However, owing to its rarity, there is no standard protocol for treating metastatic porocarcinoma. While clinicians may recommend chemotherapy or radiotherapy for the treatment of metastatic porocarcinoma, there is limited evidence to support its clinical efficacy[ 10 , 11 ].…”

“…Delayed diagnosis of porocarcinoma may postpone optimal treatment. The metastatic rate of porocarcinoma is approximately 20%-30%[ 5 , 8 , 11 ], and the mortality rate of metastatic porocarcinoma is approximately 80% or 65%-67% when it involves the lymph nodes[ 10 ]. PET-CT and CT are primarily performed for evaluating metastasis[ 8 ].…”