“…Corroborating the hypothesis that large urban centers started to experiment the increase in these diseases at an earlier time than other capital cities where the process of industrialization and urbanization took place later, Bodstein 19 and Lotufo 20 reported the importance of circulatory system pathologies and cancer among the main causes of mortality since the beginning of the 20 th century in some of the more developed capital cities, such as Sao Paulo, Rio de Janeiro, Belo Horizonte, Vitoria, Curitiba and Porto Alegre, similarly to what had been observed in England, Germany and the United States. Analyses by Laurenti and Fonseca 11 showed the expressive increase in mortality due to CAD in Sao Paulo, with a predominance of IHD at the immediate post-war period, between the decades of the 40s and 60s.…”