2017
DOI: 10.1002/bdr2.1086
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Background Elevated body core temperature has been shown to have teratogenic effects in animal studies. Our study evaluated the association between weather-related extreme heat events (EHEs) in the summer season and neural tube defects (NTDs), and further investigated whether pregnant women with a high pre-gestational body mass index (BMI) have a greater risk of having a child with NTDs associated with exposure to EHE than women with a normal BMI. Methods We conducted a population-based case-control study am… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
9
2

Year Published

2018
2018
2023
2023

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 11 publications
(11 citation statements)
references
References 39 publications
0
9
2
Order By: Relevance
“…In this study, we found that the hot climate is a risk factor for NTDs. In contrast to our study, Soim et al did not notice a significant relationship between climate and NTDs [26]. Wu et al in their nested case-control study, realized that infertility could be connected to an increased risk of spinal NTDs among infants while no statistical difference was found between the two groups in our study (P=0.78) [27].…”
Section: Discussioncontrasting
confidence: 99%
See 1 more Smart Citation
“…In this study, we found that the hot climate is a risk factor for NTDs. In contrast to our study, Soim et al did not notice a significant relationship between climate and NTDs [26]. Wu et al in their nested case-control study, realized that infertility could be connected to an increased risk of spinal NTDs among infants while no statistical difference was found between the two groups in our study (P=0.78) [27].…”
Section: Discussioncontrasting
confidence: 99%
“…The elevated body temperature during the preconceptional period will result in mitotic inhibition and subsequent genetic abnormalities in cell division. One explanation for the lack of association observed in our study may be that the core body temperature of mothers who experienced hot weather did not increase at a level that cause inhibition of the pathogenic mechanism [26].…”
Section: Discussioncontrasting
confidence: 76%
“…The search in the mapping review identified 14,880 articles after removal of duplicate records ( Figure 1 ). Overall, 2273 articles were classified as “heat-exposure studies or heat adaptation studies”, and 175 of these were selected for full text screening, with 13 eligible for this review [ 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 ]. A meta-analysis was not conducted due to considerable methodological diversity, statistical heterogeneity and the limited number of studies on each congenital defect.…”
Section: Resultsmentioning
confidence: 99%
“…In the past few decades, an increasing number of epidemiological studies have evaluated the influence of temperature exposure during pregnancy on PTB (Barreca and Schaller 2019;Carolan-Olah and Frankowska 2014;Guo et al 2018;Zhang et al 2017) and other adverse birth outcomes such as birth defects (Soim et al 2017). Most studies suggested an association between high-temperature exposure during the week prior to the delivery and PTB (Basu et al 2010;Ha et al 2017).…”
Section: Discussionmentioning
confidence: 99%