Poor WOMAC Scores in Contralateral Knee Negatively Impact TKA Outcomes: Data From the Osteoarthritis Initiative

Kahn, Timothy L.; Soheili, Aydin; Schwarzkopf, Ran

doi:10.1016/j.arth.2014.03.031

Cited by 21 publications

(11 citation statements)

References 21 publications

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“…Specifically, our patients tended to have higher WOMAC-Pain and WOMAC-Function scores than Western patients, which indicates that our patients reported having more knee pain and disability26 ) . Moreover, our patients took twice as long to perform the TUG test and only managed to walk 70% of the 6MWT distance that was walked by Western patients on average18 ) .…”

Section: Discussionmentioning

confidence: 61%

Preoperative physical performance predictors of self-reported physical function and quality of life in patients scheduled for total knee arthroplasty

et al. 2016

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[Purpose] To determine the preoperative self-reported and performance-based physical function of patients with end-stage knee osteoarthritis who awaited total knee arthroplasty. The preoperative physical performance factors that predicted self-reported physical function and quality of life were also identified. [Subjects and Methods] All adults with end-stage knee osteoarthritis awaiting surgery were enrolled. Before surgery, self-reported disease-specific physical function and self-reported pain were measured using the Western Ontario McMaster Universities Osteoarthritis Index, self-reported quality of life was measured using the EuroQOL five dimensions questionnaire, and physical performance tests were performed, the 6 minute walk test, the timed up-and-go test, instrumental gait analysis, and measurement of isometric knee flexor and extensor strength of the surgical and nonsurgical knees. [Results] In total, 55 adults (49 females; 73.3 ± 6.1 years) were included. This study showed that several preoperative self-reported and physical performance factors were predictive of self-reported physical function and quality of life. [Conclusion] In patients with end-stage knee osteoarthritis, preoperative pain and dynamic balance ability were the most powerful predictors of self-reported physical function. Preoperative pain and exercise tolerance were the most powerful predictors of quality of life. Preoperative rehabilitation strategies that focus on dynamic balance, aerobic, and resistance exercises may improve surgical outcomes.

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Section: Discussionmentioning

confidence: 61%

Preoperative physical performance predictors of self-reported physical function and quality of life in patients scheduled for total knee arthroplasty

et al. 2016

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“…If the population also includes individuals with OA at joint sites other than the index knee, the sample size should ideally be increased to permit stratified analyses of the subsets of individuals according to OA localization joints (e.g., knee and hip) with adequate statistical power. This may be particularly important since PRO responses may differ among individuals with unilateral knee OA, bilateral knee OA 28,29 , OA at other joints (e.g., hip or spine), or generalized OA. These analyses, however, can become complicated when some individuals have involvement at multiple joint regions.…”

Section: Selecting a Study Populationmentioning

confidence: 99%

OARSI Clinical Trials Recommendations: Design, conduct, and reporting of clinical trials for knee osteoarthritis

McAlindon

Driban

Henrotin

et al. 2015

Osteoarthritis and Cartilage

181

166

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The goal of this document is to update the original OARSI recommendations specifically for the design, conduct, and reporting of clinical trials that target symptom or structure modification among individuals with knee osteoarthritis (OA). To develop recommendations for the design, conduct, and reporting of clinical trials for knee OA we initially drafted recommendations through an iterative process. Members of the working group included representatives from industry and academia. After the working group members reviewed a final draft, they scored the appropriateness for recommendations. After the members voted we calculated the median score among the nine members of the working group who completed the score. The document includes 25 recommendations regarding randomization, blocking and stratification, blinding, enhancing accuracy of patient-reported outcomes (PRO), selecting a study population and index knee, describing interventions, patient-reported and physical performance measures, structural outcome measures, biochemical biomarkers, and reporting recommendations. In summary, the working group identified 25 recommendations that represent the current best practices regarding clinical trials that target symptom or structure modification among individuals with knee OA. These updated recommendations incorporate novel technologies (e.g., magnetic resonance imaging (MRI)) and strategies to address the heterogeneity of knee OA.

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“…Accordingly, early and accurate identification of at-risk patients would better direct resources toward preventive care for them. While previous cohort studies have improved our understanding of the risk factors for post-TKA functional limitations 1,2,3,4,5,6,7,8,9 , in reviewing the literature we saw that no studies, to our knowledge, have systematically integrated multiple predictors into a single, clinically practical model. Thus, to facilitate clinical and shared decision making 10 , our study aimed to develop the first multivariable prediction model to estimate the risk of post-TKA walking limitations.…”

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confidence: 99%

Development of a Prediction Model to Estimate the Risk of Walking Limitations in Patients with Total Knee Arthroplasty

et al. 2015

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Poor WOMAC Scores in Contralateral Knee Negatively Impact TKA Outcomes: Data From the Osteoarthritis Initiative

Cited by 21 publications

References 21 publications

Preoperative physical performance predictors of self-reported physical function and quality of life in patients scheduled for total knee arthroplasty

Preoperative physical performance predictors of self-reported physical function and quality of life in patients scheduled for total knee arthroplasty

OARSI Clinical Trials Recommendations: Design, conduct, and reporting of clinical trials for knee osteoarthritis

Development of a Prediction Model to Estimate the Risk of Walking Limitations in Patients with Total Knee Arthroplasty

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