Poor glycated haemoglobin control and adverse pregnancy outcomes in type 1 and type 2 diabetes mellitus: Systematic review of observational studies

Abstract

Background: Glycaemic control in women with diabetes is critical to satisfactory pregnancy outcome. A systematic review of two randomised trials concluded that there was no clear evidence of benefit from very tight versus tight glycaemic control for pregnant women with diabetes.

Breastfeeding in Women With Type 1 Diabetes

“…The literature is consistent regarding the higher occurrence of maternal and neonatal complications in mothers with diabetes ( 6 – 8 ), which was also confirmed in our study. It seems to be the higher frequency of birth-related complications that affects the breastfeeding duration.…”

Breastfeeding in Women With Type 1 Diabetes

“…The literature is consistent regarding the higher occurrence of maternal and neonatal complications in mothers with diabetes ( 6 – 8 ), which was also confirmed in our study. It seems to be the higher frequency of birth-related complications that affects the breastfeeding duration.…”

Peri-conception hyperglycaemia and nephropathy are associated with risk of congenital anomaly in women with pre-existing diabetes: a population-based cohort study

“…Peri-conception HbA 1c was the most important independent predictor of congenital anomaly risk, confirming previous reports [4][5][6]. The current study identified a linear relationship with HbA 1c for values between 6.3% and 11% (45 and 97 mmol/mol).…”

Maternal Risk Factors for Stillbirth: A Registry–Based Study

“…Diabetes can have significant impacts on maternal, fetal and neonatal. The presence of diabetes can increase the risk of stillbirth by five times, and the risk of neonatal death by three times [18,24] which is similar to our findings (OR = 2.5). Meta-analysis of 70 studies on screening and management of diabetes during pregnancy indicates that the only timing intervention associated with a significant decrease in rate of stillbirths rates occurred during the preconception period [25].…”

Breastfeeding in Women With Type 1 Diabetes

“…The literature is consistent regarding the higher occurrence of maternal and neonatal complications in mothers with diabetes ( 6 – 8 ), which was also confirmed in our study. It seems to be the higher frequency of birth-related complications that affects the breastfeeding duration.…”

Peri-conception hyperglycaemia and nephropathy are associated with risk of congenital anomaly in women with pre-existing diabetes: a population-based cohort study

“…Peri-conception HbA 1c was the most important independent predictor of congenital anomaly risk, confirming previous reports [4][5][6]. The current study identified a linear relationship with HbA 1c for values between 6.3% and 11% (45 and 97 mmol/mol).…”

Maternal Risk Factors for Stillbirth: A Registry–Based Study

“…Diabetes can have significant impacts on maternal, fetal and neonatal. The presence of diabetes can increase the risk of stillbirth by five times, and the risk of neonatal death by three times [18,24] which is similar to our findings (OR = 2.5). Meta-analysis of 70 studies on screening and management of diabetes during pregnancy indicates that the only timing intervention associated with a significant decrease in rate of stillbirths rates occurred during the preconception period [25].…”

Breastfeeding in Women With Type 1 Diabetes

“…The literature is consistent regarding the higher occurrence of maternal and neonatal complications in mothers with diabetes ( 6 – 8 ), which was also confirmed in our study. It seems to be the higher frequency of birth-related complications that affects the breastfeeding duration.…”

Peri-conception hyperglycaemia and nephropathy are associated with risk of congenital anomaly in women with pre-existing diabetes: a population-based cohort study

“…Peri-conception HbA 1c was the most important independent predictor of congenital anomaly risk, confirming previous reports [4][5][6]. The current study identified a linear relationship with HbA 1c for values between 6.3% and 11% (45 and 97 mmol/mol).…”

Maternal Risk Factors for Stillbirth: A Registry–Based Study

“…Diabetes can have significant impacts on maternal, fetal and neonatal. The presence of diabetes can increase the risk of stillbirth by five times, and the risk of neonatal death by three times [18,24] which is similar to our findings (OR = 2.5). Meta-analysis of 70 studies on screening and management of diabetes during pregnancy indicates that the only timing intervention associated with a significant decrease in rate of stillbirths rates occurred during the preconception period [25].…”