Polysaccharide-Silica Hybrids: Design and Applications

Singh, Vandana; Srivastava, Prabhat Kumar; Singh, Angela; Singh, Devendra Kumar; Malviya, Tulika

doi:10.1080/15583724.2015.1090449

Cited by 42 publications

(14 citation statements)

References 88 publications

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“…Moreover, these support materials are produced in various morphological shapes with controllable particle sizes, usually at nanoscale, which make them suitable for use with enzymes. Furthermore, these materials possess remarkable quantities of various functional groups, corresponding to the chemical groups of the proteins, which enhance enzyme binding and surface modification [78]. However, particularly during the last decade, scientific attention has been directed towards hybrid and composite materials, which combine properties of both composite precursor types and thus maximize their advantages [79].…”

Section: New Support Materials For Enzyme Immobilizationmentioning

confidence: 99%

A General Overview of Support Materials for Enzyme Immobilization: Characteristics, Properties, Practical Utility

et al. 2018

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In recent years, enzyme immobilization has been presented as a powerful tool for the improvement of enzyme properties such as stability and reusability. However, the type of support material used plays a crucial role in the immobilization process due to the strong effect of these materials on the properties of the produced catalytic system. A large variety of inorganic and organic as well as hybrid and composite materials may be used as stable and efficient supports for biocatalysts. This review provides a general overview of the characteristics and properties of the materials applied for enzyme immobilization. For the purposes of this literature study, support materials are divided into two main groups, called Classic and New materials. The review will be useful in selection of appropriate support materials with tailored properties for the production of highly effective biocatalytic systems for use in various processes.

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Section: New Support Materials For Enzyme Immobilizationmentioning

confidence: 99%

A General Overview of Support Materials for Enzyme Immobilization: Characteristics, Properties, Practical Utility

et al. 2018

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“…Then the polysaccharide templates are used to prepare inorganic crystal materials having different structures and unique properties. [123] At present, polysaccharides have been used as templates to induce and regulate the growth of many inorganic crystals, such as calcium carbonate, [124] iron-containing minerals, [123b] silica, [125] nanoselenium, [126] calcium phosphate, [127] metals, [128] and metal oxides. [129] Polysaccharide-based biomimetic mineralized nanoparticles generally have good biocompatibility, biodegradability, and high productivity with rich sources.…”

Section: Regulation Of Biomineralization By Polysaccharide Templatesmentioning

confidence: 99%

Biomineralization: An Opportunity and Challenge of Nanoparticle Drug Delivery Systems for Cancer Therapy

Wang

Liu

Zheng

et al. 2020

Adv Healthcare Materials

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Biomineralization is a common process in organisms to produce hard biomaterials by combining inorganic ions with biomacromolecules. Multifunctional nanoplatforms are developed based on the mechanism of biomineralization in many biomedical applications. In the past few years, biomineralization-based nanoparticle drug delivery systems for the cancer treatment have gained a lot of research attention due to the advantages including simple preparation, good biocompatibility, degradability, easy modification, versatility, and targeting. In this review, the research trends of biomineralization-based nanoparticle drug delivery systems and their applications in cancer therapy are summarized. This work aims to promote future researches on cancer therapy based on biomineralization. Rational design of nanoparticle drug delivery systems can overcome the bottleneck in the clinical transformation of nanomaterials. At the same time, biomineralization has also provided new research ideas for cancer treatment, i.e., targeted therapy, which has significantly better performance.

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“…Inspired by this, the biomimetic synthesis of silica-relevant hybrid materials using chitosan as a template via the silica biomineralization processes is attracting an increasing amount of attention, and the solution-gelatin (sol-gel) technique is a universal mineralization technique [ 85 , 86 , 100 ]. The sol-gel method is indeed a wet-chemical technique with two reactions: hydrolysis and polycondensation [ 101 ]. In general, polymeric molecules and metal-organic alkoxides, especially tetramethoxysilane (TMOS) and tetraethoxysilane (TEOS), are sol precursors to silicates, and the final gel of an integrated three-dimensional network structure can be obtained by sol-gel transition [ 102 ].…”

Section: Chitosan-based Biomimetically Mineralized Composite Matermentioning

confidence: 99%

Chitosan-Based Biomimetically Mineralized Composite Materials in Human Hard Tissue Repair

Ren

et al. 2020

Molecules

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Chitosan is a natural, biodegradable cationic polysaccharide, which has a similar chemical structure and similar biological behaviors to the components of the extracellular matrix in the biomineralization process of teeth or bone. Its excellent biocompatibility, biodegradability, and polyelectrolyte action make it a suitable organic template, which, combined with biomimetic mineralization technology, can be used to develop organic-inorganic composite materials for hard tissue repair. In recent years, various chitosan-based biomimetic organic-inorganic composite materials have been applied in the field of bone tissue engineering and enamel or dentin biomimetic repair in different forms (hydrogels, fibers, porous scaffolds, microspheres, etc.), and the inorganic components of the composites are usually biogenic minerals, such as hydroxyapatite, other calcium phosphate phases, or silica. These composites have good mechanical properties, biocompatibility, bioactivity, osteogenic potential, and other biological properties and are thus considered as promising novel materials for repairing the defects of hard tissue. This review is mainly focused on the properties and preparations of biomimetically mineralized composite materials using chitosan as an organic template, and the current application of various chitosan-based biomimetically mineralized composite materials in bone tissue engineering and dental hard tissue repair is summarized.

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Polysaccharide-Silica Hybrids: Design and Applications

Cited by 42 publications

References 88 publications

A General Overview of Support Materials for Enzyme Immobilization: Characteristics, Properties, Practical Utility

A General Overview of Support Materials for Enzyme Immobilization: Characteristics, Properties, Practical Utility

Biomineralization: An Opportunity and Challenge of Nanoparticle Drug Delivery Systems for Cancer Therapy

Chitosan-Based Biomimetically Mineralized Composite Materials in Human Hard Tissue Repair

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