Polymorphic ventricular tachycardia associated with an episode of reflex syncope: Is this the needle in the haystack?

Tester, Matthew A.; Hockin, Brooke C. D.; David, Thuso; Franciosi, Sonia; Harris, Kevin C.; Claydon, Victoria E.; Sanatani, Shubhayan

doi:10.1016/j.hrcr.2018.07.013

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…BrS manifests under conditions of high vagal tone. ANS testing in an adolescent patient whose pacemaker recorded PVT at the time of a syncopal event revealed impaired vagal and sympathetic baroreflex function which likely contributed to the arrhythmia 58 .…”

Section: Autonomic Nervous Systemmentioning

confidence: 99%

Sudden Cardiac Arrest in the Paediatric Population

Franciosi

Abrams

Ingles

et al. 2022

CJC Pediatric and Congenital Heart Disease

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Section: Autonomic Nervous Systemmentioning

confidence: 99%

Sudden Cardiac Arrest in the Paediatric Population

Franciosi

Abrams

Ingles

et al. 2022

CJC Pediatric and Congenital Heart Disease

Self Cite

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Initially unexplained cardiac arrest in children and adolescents: A national experience from the Canadian Pediatric Heart Rhythm Network

et al. 2020

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Blood pressure variability at rest and during pressor challenges in patients with acute ischemic stroke

Roy,

Lam,

Panerai

et al. 2024

Blood Pressure Monitoring

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Introduction Patients with acute ischemic stroke (AIS) have elevated blood pressure (BP) variability (BPV) and reduced baroreflex sensitivity (BRS) at rest for several days after initial stroke symptoms. We aimed to assess BPV and BRS in AIS patients during pressor challenge maneuvers in the acute and subacute phases of stroke. Pressor challenge maneuvers simulate day-to-day activities and can predict the quality of life. Methods Continuous beat-to-beat BP and ECG in 15 AIS patients (mean age 69 ± 7.5 years) and 15 healthy controls (57 ± 16 years) were recorded at rest and during a 5-min rapid head positioning (RHP) paradigm. Patients were assessed within 24 h (acute phase) and 7 days (subacute phase) of stroke onset. Low frequency (LF) SBP power (measure of BPV), LF-α, and combined α-index (measure of BRS) were calculated from the recordings. Results In the acute phase, at rest, LF-SBP power was higher (P = 0.024) and α-index was lower (P = 0.006) in AIS patients than in healthy controls. There was no change in LF-SBP during RHP in the patients but in healthy controls, it increased significantly (P = 0.018). In the subacute phase, at rest, the alpha-index increased (P = 0.037) and LF-SBP decreased (P = 0.029) significantly in the AIS patients, however, there was still no rise in the LF-SBP power during RHP (P = 0.240). Conclusion AIS patients have a high resting BPV. High resting BPV may be responsible for blunted BPV responses during pressor challenge maneuvers such as RHP, suggesting ongoing autonomic dysfunction and compromised quality of life.

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Polymorphic ventricular tachycardia associated with an episode of reflex syncope: Is this the needle in the haystack?

Cited by 3 publications

References 15 publications

Sudden Cardiac Arrest in the Paediatric Population

Sudden Cardiac Arrest in the Paediatric Population

Initially unexplained cardiac arrest in children and adolescents: A national experience from the Canadian Pediatric Heart Rhythm Network

Blood pressure variability at rest and during pressor challenges in patients with acute ischemic stroke

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