Polymeric Nanoparticles

Guterres, Silvia; Paese, Karina; Pohlmann, Adriana Raffin

doi:10.1007/978-3-030-16573-4_5

Cited by 3 publications

(4 citation statements)

References 64 publications

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“…Owing to the defined chemical structure, synthetic polymers offer control over their physical and chemical properties compared to natural polymers. Conversely, bio-based polymeric nanoencapsulations offer key advantages for use in biomedical applications as they present remarkable biocompatibility across a wide range of concentrations and are often cost-effective [ 137 ]. In nanomedicine, these polymers predominantly fall into two subcategories: polysaccharides and proteins.…”

Section: Anthocyanin-based Polymers For Healthcare Applicationsmentioning

confidence: 99%

Anthocyanin-Loaded Polymers as Promising Nature-Based, Responsive, and Bioactive Materials

Rosales-Murillo,

Sánchez-Bodón,

Hernández Olmos

et al. 2024

Polymers

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Anthocyanins are a specific group of molecules found in nature that have recently received increasing attention due to their interesting biological and colorimetric properties that have been successfully applied in several fields such as food preservation and biomedicine. Consequently, reviews devoted to a general overview of these flavonoids have proliferated in recent years. Meanwhile, the incorporation of anthocyanins into polymeric systems has become an interesting strategy to widen the applicability of these molecules and develop new smart and functional polymers in the above cited areas. However, anthocyanin-based polymers have been scarcely reviewed in the literature. Accordingly, this review aims to be a systematic summary of the most recent approaches for the incorporation of anthocyanins into macro-, micro-, or nanostructured polymers. Moreover, this work describes the fundamentals of the applicability of smart anthocyanin-based polymers and offers an updated review of their most interesting applications as sensors, biological regulators, and active materials.

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Section: Anthocyanin-based Polymers For Healthcare Applicationsmentioning

confidence: 99%

Anthocyanin-Loaded Polymers as Promising Nature-Based, Responsive, and Bioactive Materials

Rosales-Murillo,

Sánchez-Bodón,

Hernández Olmos

et al. 2024

Polymers

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“…In this sense, conventionally used for drug delivery, polymeric nanocapsules can be used to protect the bioactives present in EOs and VOs and optimize the performance of the cosmetics, through sustained releasing of actives, decreasing of toxicity, greater penetration capacity and better distribution in the skin layers (GUTERRES, 2019;BEGNES, 2020).…”

Section: Nanoencapsulation Of Essential and Vegetable Oils To Obtain ...mentioning

confidence: 99%

“…PNs synthesis methods can be based on the polymerization of monomers (in situ polymerization), where polymers are formed simultaneously with nanoparticles; or methods that work with the dispersion and precipitation of preformed polymers, which are more commonly used. The polymer and the obtaining techniques influence the structure, the physical-chemical properties of the PNs, the inclusion efficiency and the active release kinetics (CASANOVA, 2016;GUTERRES, 2019).…”

Section: Nanoencapsulation Of Essential and Vegetable Oils To Obtain ...mentioning

confidence: 99%

Nanoencapsulation of essential and vegetable oils to obtain polymeric nanoparticles for dermocosmetics application

Januário¹,

Iulianelli²

2023

Ciências Da Saúde E Suas Descobertas Científicas

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Essential and vegetable oils are rich in bioactives, which can act on the skin through their therapeutic properties. However, they are often sensitive to oxidation and degradation, making it necessary to use resources for their protection. The nanoencapsulation of these oils allows bioactives to have their properties protected and optimized through the sustained release of actives, reduced toxicity, and even greater penetration capacity and better distribution in the skin layers, enhancing their effects. Polymeric nanoparticles, particularly, have shown important results for delivery of bioactives to the skin, and can be produced from natural or synthetic polymers, which present biocompatibility and biodegradability. The main methods for obtaining these nanostructured materials are nanoprecipitation, coacervation and ionic gelation, and these methods are the scope of this literature review.

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“…They have also got the ability to by passes RES and phagocytosis by macrophages and by using different ligands on the surface of polymer of nanoparticles drug targeting on a particular tumor can be achieved. Nanoparticles have been found to show enhanced permeation and retention (EPR) of the encapsulated drug [11,12].…”

Section: Why Polymeric Nanoparticles?mentioning

confidence: 99%

Oral Formulation of Paclitaxel and Erlotinib Polymeric Nanoparticles: A Potential Combination to Treat Breast Cancer

Iqbal¹

2020

BJSTR

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Cancer treatment continues to remain a challenge and requires concerted efforts towards designing and development of newer forms of drug delivery systems. Concurrently, the practitioners are in a process of testing singular as well as combination of old and new APIs commensurate to the treatment challenges associated with specific type of cancer forms. Till recently, as reported, by many researchers polymeric nanoparticles were only exploited to encapsulate single drugs, but cognizance of clinical evidence for fruitful use of anticancer drug combinations, has yielded, many research reports of co-encapsulating two or more active moieties but not without formulation difficulties. Foremost, the inherent pharmacotechnical challenges of an anticancer drug invariably makes its formulation a difficult premise, additionally co-encapsualting two different drugs adds onto this challenge. Moreover the physiological limitation like susceptibility to Pgp efflux cannot be ignored. Keeping all these facts into consideration a stable nanoformulation of paclitaxel and erlotinib (PE-NPs) could be developed and sequentially optimized.

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Polymeric Nanoparticles

Cited by 3 publications

References 64 publications

Anthocyanin-Loaded Polymers as Promising Nature-Based, Responsive, and Bioactive Materials

Anthocyanin-Loaded Polymers as Promising Nature-Based, Responsive, and Bioactive Materials

Nanoencapsulation of essential and vegetable oils to obtain polymeric nanoparticles for dermocosmetics application

Oral Formulation of Paclitaxel and Erlotinib Polymeric Nanoparticles: A Potential Combination to Treat Breast Cancer

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