Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds

Mondschein, Ryan J.; Kanitkar, Akanksha; Williams, Christopher B.; Verbridge, Scott S.; Long, Timothy Edward

doi:10.1016/j.biomaterials.2017.06.005

Cited by 378 publications

(314 citation statements)

References 186 publications

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“…Indeed, SLA has proven as a fast, stable, mask‐less, and layer‐by‐layer additive process, with significant ability of building truly 3D, high‐aspect‐ratio, and light‐weight microscale and mesoscale structures . Similar to SLS, SLA too has noticeable scope for the biomedical applications as it can utilize both natural and synthetic polymers . However, retaining the degradability and mechanical properties is of utmost importance for available polymers.…”

Section: Dp Technologies For Pmc Systemsmentioning

confidence: 99%

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3D Printing of polymer composites: A short review

Singh

Ramakrishna

Berto

2019

Mat Design & Process Comms

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Composite or reinforced materials, especially in the class of polymers, are becoming prominent materials for the diversified range of engineering and scientific utilities because of their physical, chemical, mechanical, and structural excellences. Indeed, the main credit for the widespread acknowledgment of polymer matrix composites (PMCs) goes to the various types of natural and synthetic reinforcements, which resulted in good interfacial chemistries. However, the intrinsic challenges of traditional manufacturing technologies always presented restrictions in the development of application specific PMCs. Reportedly, with an evolution of three‐dimensional printing (3DP) technologies, the applications of PMCs have been transformed as these enabled the production of near‐net shapes with high degree of control over the design, reinforcements, and processing parametric while maintaining the waste associated at minimal level. However, the industrial benefits of 3DP technologies for still limited owing to the lack of awareness among the young professionals and industrialists. Moreover, the literature available in this regard is either too scattered making it tedious for the professionals to go through or limited to only fundamental concepts. Therefore, the concept of this review paper is to provide brief research‐based insights of different 3DP technologies (namely, fused deposition modeling, selective laser sintering, stereolithography, laminated object manufacturing, and inkjet printing), material systems, applications, and the future paradigms of research as a short and precise document.

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Section: Dp Technologies For Pmc Systemsmentioning

confidence: 99%

“…108 Similar to SLS, SLA too has noticeable scope for the biomedical applications as it can utilize both natural and synthetic polymers. 75 However, retaining the degradability and mechanical properties is of utmost importance for available polymers. Kalsoom et al 41…”

Section: Stereolithographymentioning

confidence: 99%

3D Printing of polymer composites: A short review

Singh

Ramakrishna

Berto

2019

Mat Design & Process Comms

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“…Various parameters such as polymer composition, crosslink density, degree of crystallinity, and scaffold additives have profound influence on scaffold degradation rates. Poly( d,l ‐lactide) (PLA), poly(glycolide), and copolymers are common hard tissue engineering scaffolds because they result in tough and mechanically strong materials …”

Section: Polymersmentioning

confidence: 99%

“…Detailed reviews of natural polymers have been published elsewhere . The combination of the mechanical properties of synthetic polymers with the biological properties of natural polymer presents best option of combining the desired mechanical properties with biological properties to fabricate functional tissue engineering scaffolds …”

Section: Polymersmentioning

confidence: 99%

Multifaceted polymeric materials in three‐dimensional processing (3DP) technologies: Current progress and prospects

Oderinde

Kang

et al. 2018

Polymers for Advanced Techs

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Three‐dimensional printing (3DP) technologies, which are sets of powerful deposition methods employed to fabricate 3D objects with materials in the fields of material sciences and engineering, biomedical and biocompatible structural components, automotive, aviation, and polymers, among others, are currently rapidly developing manufacturing technologies. The methods have significant advantages, which include designing flexibility, enhanced geometrical freedom, low cost, and net shape manufacture, among others, over the traditional “subtractive” method. This review highlights the major 3D printing techniques, especially in the fields of advanced polymeric material fabrication and engineering, as well as the synergy in the incorporation of different types of polymeric materials and composites in a process that will lead to an enhancement of dimensional accuracy for 3D technologies. Furthermore, composite ink systems especially polymer‐based and hydrogel‐based in tissue engineering applications are also discussed.

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“…Most regenerative strategies rely on the use of tissue substitutes, which act as scaffolds to stabilize the blood clot and promote and support the organization of a provisional matrix that will eventually allow the ingrowth of progenitors cells from neighbouring tissues and the deposition of novel tissue [1][2][3][4]. To achieve this ambitious goal biomaterials must provide a favourable microenvironment that is conductive to cell attachment, proliferation and to the expression of an adequate cell phenotype for the formation of the desired tissue.…”

mentioning

confidence: 99%