Polyglandular autoimmune syndrome and anorexia nervosa

Abstract

The first case of polyglandular autoimmune syndrome (PAS) in a patient with anorexia nervosa is reported. The association of pernicious anemia with vitiligo and endocrine hypofunction (PAS) is reviewed. Eating disorder patients with B12 deficiency who have vitiligo or a history of endocrine hypofunction should have a Schilling test to exclude pernicious anemia. © 1994 by John Wiley & Sons, Inc.

Prevalence of psychiatric comorbidities and treatment initiation in African American pediatric patients with vitiligo: A retrospective, single-center, case-control study

“…Autoimmune polyglandular syndromes, which involve multiple endocrine gland failures, could provide a biological basis for the co-occurrence of these conditions. 25 This association warrants further investigation, as understanding the autoimmune components could lead to more comprehensive treatment strategies for affected individuals.…”

Prevalence of psychiatric comorbidities and treatment initiation in African American pediatric patients with vitiligo: A retrospective, single-center, case-control study

“…Autoimmune polyglandular syndromes, which involve multiple endocrine gland failures, could provide a biological basis for the co-occurrence of these conditions. 25 This association warrants further investigation, as understanding the autoimmune components could lead to more comprehensive treatment strategies for affected individuals.…”

Immune-mediated animal models of Tourette syndrome

“…Immune and infectious factors are implicated in the pathogenesis of TS (Martino et al, 2009a; Murphy et al, 2010a; Singer, 2011) and a wide range of related neuropsychiatric disorders arising in childhood, including obsessive-compulsive disorder (OCD) (Gray and Bloch, 2012; Murphy et al, 2006; Rotge et al, 2010), autism spectrum disorders (ASD) (Fox et al, 2012; Goines and Ashwood, 2012; Harvey and Boksa, 2012; Hollander et al, 1999; Margutti et al, 2006; Needleman and McAllister, 2012), attention-deficit/hyperactivity disorder (AD/HD)(Peterson et al, 2000; Rout et al, 2012; Toto et al, 2012) and anorexia nervosa (Favaro et al, 2011; Henry et al, 1999; Holden and Pakula, 1996; Kam et al, 1994; Sokol, 2000; Sokol et al, 2002). Overlap of a subset of these disorders with the prototypical, infection-related, autoimmune brain disorder, Sydenham chorea (SC), led to the application of the acronym PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection, to cases wherein illness follows infection with β-hemolytic Group A Streptococcus (GAS) (Leonard and Swedo, 2001; Swedo and Grant, 2005; Swedo et al, 1998; Swedo et al, 1994; Swedo et al, 2010).…”

Prevalence of psychiatric comorbidities and treatment initiation in African American pediatric patients with vitiligo: A retrospective, single-center, case-control study

“…Autoimmune polyglandular syndromes, which involve multiple endocrine gland failures, could provide a biological basis for the co-occurrence of these conditions. 25 This association warrants further investigation, as understanding the autoimmune components could lead to more comprehensive treatment strategies for affected individuals.…”

Immune-mediated animal models of Tourette syndrome

“…Immune and infectious factors are implicated in the pathogenesis of TS (Martino et al, 2009a; Murphy et al, 2010a; Singer, 2011) and a wide range of related neuropsychiatric disorders arising in childhood, including obsessive-compulsive disorder (OCD) (Gray and Bloch, 2012; Murphy et al, 2006; Rotge et al, 2010), autism spectrum disorders (ASD) (Fox et al, 2012; Goines and Ashwood, 2012; Harvey and Boksa, 2012; Hollander et al, 1999; Margutti et al, 2006; Needleman and McAllister, 2012), attention-deficit/hyperactivity disorder (AD/HD)(Peterson et al, 2000; Rout et al, 2012; Toto et al, 2012) and anorexia nervosa (Favaro et al, 2011; Henry et al, 1999; Holden and Pakula, 1996; Kam et al, 1994; Sokol, 2000; Sokol et al, 2002). Overlap of a subset of these disorders with the prototypical, infection-related, autoimmune brain disorder, Sydenham chorea (SC), led to the application of the acronym PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection, to cases wherein illness follows infection with β-hemolytic Group A Streptococcus (GAS) (Leonard and Swedo, 2001; Swedo and Grant, 2005; Swedo et al, 1998; Swedo et al, 1994; Swedo et al, 2010).…”

Prevalence of psychiatric comorbidities and treatment initiation in African American pediatric patients with vitiligo: A retrospective, single-center, case-control study

“…Autoimmune polyglandular syndromes, which involve multiple endocrine gland failures, could provide a biological basis for the co-occurrence of these conditions. 25 This association warrants further investigation, as understanding the autoimmune components could lead to more comprehensive treatment strategies for affected individuals.…”

Immune-mediated animal models of Tourette syndrome

“…Immune and infectious factors are implicated in the pathogenesis of TS (Martino et al, 2009a; Murphy et al, 2010a; Singer, 2011) and a wide range of related neuropsychiatric disorders arising in childhood, including obsessive-compulsive disorder (OCD) (Gray and Bloch, 2012; Murphy et al, 2006; Rotge et al, 2010), autism spectrum disorders (ASD) (Fox et al, 2012; Goines and Ashwood, 2012; Harvey and Boksa, 2012; Hollander et al, 1999; Margutti et al, 2006; Needleman and McAllister, 2012), attention-deficit/hyperactivity disorder (AD/HD)(Peterson et al, 2000; Rout et al, 2012; Toto et al, 2012) and anorexia nervosa (Favaro et al, 2011; Henry et al, 1999; Holden and Pakula, 1996; Kam et al, 1994; Sokol, 2000; Sokol et al, 2002). Overlap of a subset of these disorders with the prototypical, infection-related, autoimmune brain disorder, Sydenham chorea (SC), led to the application of the acronym PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection, to cases wherein illness follows infection with β-hemolytic Group A Streptococcus (GAS) (Leonard and Swedo, 2001; Swedo and Grant, 2005; Swedo et al, 1998; Swedo et al, 1994; Swedo et al, 2010).…”