Polydimethylsiloxane Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Long-Term Results

Mattioli, Francesco; Bettini, Margherita; Botti, Cecilia; Busi, Giulia; Tassi, Sauro; Malagoli, Andrea; Molteni, Gabriele; Trebbi, Marco; Luppi, Marcello; Bergamini, Giuseppe; Presutti, Livio

doi:10.1016/j.jvoice.2016.12.017

Cited by 18 publications

(10 citation statements)

References 34 publications

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“…The patients in the present study reported significant improvement in their perceived voice in the 1st follow-up (after 1 week), and this improvement continued after 3 months as reported in the 2nd follow-up as evident from their VHI scores. These results come in agreement with Mohammed et al [28] and Mattioli et al [23] who also reported significant improvement in both immediate and long term follow-up assessments.…”

Section: Discussionsupporting

confidence: 91%

“…Iatrogenic cause was the cause of VFP in the majority of patients (60%) followed by idiopathic cause (40%). This finding is close to that reported by a number of previous studies such as Morgan et al [21], Rudolf and Sibylle [22], and Mattioli et al [23] who also concluded that iatrogenic causes including thyroidectomy and thoracic surgery were the commonest causes of VFP.…”

Section: Discussionsupporting

confidence: 91%

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Respiratory and voice outcomes of office-based injection laryngoplasty in patients with unilateral vocal fold paralysis

Elsaeed

Afsah

Moneir

et al. 2021

Egypt J Otolaryngol

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Background Injection laryngoplasty is a surgical procedure used in management of glottal insufficiency. The objective of this study was to assess respiratory and voice outcomes of office-based injection laryngoplasty in patients with unilateral vocal fold paralysis (UVFP). Ten patients underwent office-based injection via transcutaneous approach using Radiesse or hyaluronic acid. Auditory perceptual assessment (APA), voice handicap index (VHI), size of the glottic gap, acoustic parameters (jitter, shimmer, and harmonic to noise ratio), maximum phonation time (MPT), stroboscopic evaluation, pulmonary function tests (PFTs), and videofluoroscopic evaluation of swallowing were done pre-injection, 1 week and 3 months post-injection. Results Subjective and objective voice outcomes, in addition to laryngostroboscopic parameters improved after injection. Non-significant difference was found between pre- and post-injection results of the PFTs. Conclusions Office-based injection laryngoplasty is a safe and effective method for treating UVFP. Patients with glottic gap (< 1–3 mm) are perfect candidates for such procedure. Injection laryngoplasty improves patients’ voice quality and does not impair respiration.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 91%

Respiratory and voice outcomes of office-based injection laryngoplasty in patients with unilateral vocal fold paralysis

Elsaeed

Afsah

Moneir

et al. 2021

Egypt J Otolaryngol

View full text Add to dashboard Cite

show abstract

“…These results are consistent with those of a previous study [28]. In other studies, the post-IL patient groups tended to have lower normalized scores, and significant improvements were observed in GRBAS, MPT, CPPS, closed quotient (CQ), voice range profile, semi-tone range, and VHI-10 scores [29,30].…”

Section: Discussionsupporting

confidence: 91%

Effects of Injection Laryngoplasty with Hyaluronic Acid in Patients with Vocal Fold Paralysis

Kim

Lee

et al. 2018

Osong Public Health Res Perspect

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ObjectivesThe purpose of this study was to explore the effects of injection laryngoplasty (IL) with hyaluronic acid in patients with vocal fold paralysis (VFP).MethodsA total of 50 patients with VFP participated in this study. Pre- and post-IL assessments were performed, which included analyzing the sustained vowel /a/ phonation, and the patient reading 1 Korean sentence from the “Walk” passage that comprised 25 syllables in 10 words. To investigate the effect of IL on vocal fold function, acoustic analysis (acoustic voice quality index, cepstral peak prominence, maximum phonation time, speaking fundamental frequency) was conducted and auditory-perceptual (grade and overall severity), visual judgment (gap), and self-questionnaire (voice handicap index-10) assessments were performed.ResultsThe patients with VFP showed statistically significant differences between pre-and post-IL assessments for acoustic and auditory-perception, visual judgment, and self-questionnaire assessments.ConclusionThe patients with VFP showed positive change in vocal fold function between pre- and post-IL measurements. The findings showed that IL with hyaluronic acid is an effective method to improve vocal fold function in patients with VFP.

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“…It was found that the commonest cause of UVFP in our study was iatrogenic (thyroid and other neck surgeries) (47.1%) and the second most common cause was idiopathic (17.6%). This was in agreement with Rudolf and Sibylle [26] and Mattioli et al [27]. However, Alghonaim et al [28] reported that the majority of patients had UVFP secondary to malignant etiology followed by iatrogenic etiologies.…”

Section: Voice Outcome Assessment After Injection Laryngoplastysupporting

confidence: 87%

Outcomes versus complications in patients undergoing different modalities of injection laryngoplasty

Darweesh

El-Gazzar

Sarag

et al. 2021

Egypt J Otolaryngol

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Background Glottal insufficiency results in glottal gap between the two vocal folds, which in turn might cause dysphonia, dysphagia, and breathing problems. Vocal fold injection is considered a safe, reliable, and highly effective method of treatment. The purpose of the present study was to assess voice outcomes and complication rates in patients with glottal insufficiency undergoing injection laryngoplasty (IL) under local versus general anesthesia before, 1 week then 1 month after IL. Results Examined patients were 13 males and 12 females, suffering from dysphonia due to glottal insufficiency with mean age 43.68 ± SD 14.55. Unilateral vocal fold paralysis (UVFP) was diagnosed in seventeen cases, vocal fold scarring in six cases, presbylarynx in one case, and sulcus vocalis in one case. IL was performed in 18 cases under local anesthesia, and 7 under general anesthesia. Hyaluronic acid was injection material in 23 cases and calcium hydroxylapatite in two cases. IL by either local or general anesthesia has improved the patients’ auditory perceptual analysis of voice quality as assessed by “GRBAS” scale and Voice Handicap Index (VHI). There were four (16% of all injections) minor and self-limited complications (12% under local and 4% under general anesthesia). Conclusion Injection laryngoplasty performed under local and general anesthesia offers similar voice outcomes, but with slightly higher self-limited complications in IL under local anesthesia.

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Polydimethylsiloxane Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Long-Term Results

Cited by 18 publications

References 34 publications

Respiratory and voice outcomes of office-based injection laryngoplasty in patients with unilateral vocal fold paralysis

Respiratory and voice outcomes of office-based injection laryngoplasty in patients with unilateral vocal fold paralysis

Effects of Injection Laryngoplasty with Hyaluronic Acid in Patients with Vocal Fold Paralysis

Outcomes versus complications in patients undergoing different modalities of injection laryngoplasty

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