Polydimethylsiloxane Composites for Optical Ultrasound Generation and Multimodality Imaging

Noimark, Sacha; Colchester, Richard J.; Poduval, Radhika K.; Maneas, Efthymios; Alles, Erwin J.; Zhao, Tianrui; Zhang, Edward; Ashworth, Michael; Tsolaki, Elena; Chester, Adrian H.; Latif, Najma; David, Anna L.; Ourselin, Sébastien; Beard, Paul C.; Parkin, Ivan P.; Papakonstantinou, Ioannis; Desjardins, Adrien E.

doi:10.1002/adfm.201704919

Cited by 102 publications

(175 citation statements)

References 109 publications

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“…Recently, an all-optical alternative to electronic ultrasound transducers has been presented that uses light to both transmit and receive ultrasound. Using fibre optic technology, optical ultrasound sources [3][4][5][6][7][8] and detectors [9][10][11][12][13][14] are readily miniaturised, exhibit high bandwidths and sensitivities, and are immune to electromagnetic interference. Recently, a benchtop system has been demonstrated that used a single fibre optic ultrasound detector and a centimetre-scale monolithic photoacoustic ultrasound generator membrane to achieve video-rate two-dimensional imaging [15].…”

Section: Introductionmentioning

confidence: 99%

Source Density Apodization: Image Artifact Suppression Through Source Pitch Nonuniformity

Alles

Desjardins

2020

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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Section: Introductionmentioning

confidence: 99%

Source Density Apodization: Image Artifact Suppression Through Source Pitch Nonuniformity

Alles

Desjardins

2020

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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“…One advantage of the OpUS modality is the ability to integrate complementary modalities by tailoring the optical absorption profile of the ultrasound generating surface. 15 Previously this has been used to demonstrate co-registered ultrasound and photoacoustic imaging, but could be easily tailored to provide laser ablation through the same optical fibre as ultrasound generation.…”

Section: Resultsmentioning

confidence: 99%

Large area all-optical ultrasound imaging using robotic control

Colchester¹,

Alles²,

Dwyer³

et al. 2019

Opto-Acoustic Methods and Applications in Biophotonics IV

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In this study we report the integration of an all-optical ultrasound probe and robotic manipulator. The alloptical ultrasound probe comprised two optical fibres, a MWCNT/PDMS composite coated multimode fibre for ultrasound generation, and a concave Fabry-Pérot fibre optic hydrophone for ultrasound reception. The ultrasound probe generated pressures in excess of 2 MPa at 1.5 mm, with a corresponding −6 dB bandwidth of ca. 30 MHz. The probe was built into a rigid endoscope (outer diameter: 5 mm, length: 300 mm) and mounted on a robotic manipulator. Ultrasound A-lines were acquired during robot manipulation in order to reconstruct a 3D image which was displayed as a point cloud. Large area images (80 × 80 mm) of a tissue mimicking gel wax phantom where acquired and displayed in real-time. This work demonstrates the potential for integrating miniature fibre optic ultrasound devices with robotics.

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“…Moreover, there is a significant progress in high‐resolution imaging based on photoacoustic transmitters. Two recent review articles cover high‐resolution imaging …”

Section: Photoacoustic Transmitters For Novel Applicationsmentioning

confidence: 99%

Efficient Photoacoustic Conversion in Optical Nanomaterials and Composites

Lee

Baac

et al. 2018

Advanced Optical Materials

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approaches. While addressing the limitations of the electrical counterparts (e.g., massive amounts of radio frequency (RF) cabling and electromagnetic (EM) interference), a photoacoustic approach for gene rat ing high-amplitude ultrasound has created new opportunities.Active research on efficient photo acoustic materials has started with the development of photoacoustic contrast mediums (e.g., exogenous contrast particles) for contrast enhancement. [3][4][5] Recent advances in nanofabrication technologies have allowed to develop more efficient photoacoustic contrast mediums, [3] such as metal nanoparticles having enhanced optical absorption due to optical resonance. Later, by coating such nanoparticles on a flat substrate, layered structures were developed for generating high-amplitude ultrasound. Among many nanoparticles, gold nanoparticles were widely used owing to strong resonance. [6] In fact, these initial efforts to increase photoacoustic conversion were focused on increasing light absorption, while the critical role of thermal expansion for photoacoustic generation were often overlooked.To enhance thermal expansion for photoacoustic generation, researchers have started to fabricate composite materials, composed of light-absorbing materials mixed with polymers with high thermal expansion coefficients. These polymer-based composites significantly enhance photoacoustic conversion efficiency. Among many polymers, polydimethylsiloxane (PDMS) is exclusively used because of its high thermal expansion, optical transparency, and acoustic impedance comparable to that of water. [7][8][9][10][11] Photoacoustic pulses generated with PDMSbased composites have the characteristics of high amplitude and high frequency, which have enabled interesting applications such as cavitation-based therapy [12] and imaging. [13] For photoacoustic composites, there are a myriad of light-absorbing nanomaterials such as metal absorbers [6] and carbon nanomaterials (e.g., carbon black (CB), [14] carbon nanotube (CNT), [7,10] carbon nanofiber (CNF), [9] candle soot (CS), [8] and reduced graphene oxide (rGO) [15] ). These light-absorbing materials of nanometer sizes have an advantage over microscale absorbing materials [7] in facilitating heat transfer from the light absorbers into the surrounding mediums. Such facilitated heat transfer is another key factor that contributes to photoacoustic energy conversion.In this Review, we will start with general considerations of photoacoustic generation in nanomaterial composites. Various photoacoustic composites enabling interesting applications will be introduced. In addition, recent efforts will be reviewed from an application perspective. Also, we will discuss outlook and future directions.Photoacoustic pulses generated by pulsed laser irradiation have the characteristics of high frequency and wide bandwidth, which are desirable for imaging and sensing. Efficient photoacoustic composites have been developed for fabricating photoacoustic transmitters capable of generating highamplitude ultrasound....

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Polydimethylsiloxane Composites for Optical Ultrasound Generation and Multimodality Imaging

Cited by 102 publications

References 109 publications

Source Density Apodization: Image Artifact Suppression Through Source Pitch Nonuniformity

Source Density Apodization: Image Artifact Suppression Through Source Pitch Nonuniformity

Large area all-optical ultrasound imaging using robotic control

Efficient Photoacoustic Conversion in Optical Nanomaterials and Composites

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