Polychlorinated biphenyl contamination of nursing mothers' milk in Michigan.

Wickizer, Thomas M.; Brilliant, Lawrence B.; Copeland, Rob; Tilden, Robert L.

doi:10.2105/ajph.71.2.132

Cited by 62 publications

(12 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Children of farm and migrant workers could be From Jacobson et al ( 1989 ) and Kuwabara et al ( 1978 ) . Similar findings were reported by Yakushiji et al ( 1984 ) , Eyster et al ( 1983 ) , Wolff ( 1983 ) , Mes et al ( 1984 ) , Wickizer et al ( 1981 ) and Niessen et al ( 1984 ) . Wolff et al ( 1982 ) .…”

Section: Pesticidessupporting

confidence: 90%

Environmental contaminants in human milk

Anderson

Wolff

2000

J Expo Sci Environ Epidemiol

View full text Add to dashboard Cite

Section: Pesticidessupporting

confidence: 90%

Environmental contaminants in human milk

Anderson

Wolff

2000

J Expo Sci Environ Epidemiol

View full text Add to dashboard Cite

“…In one of the studies, a variety offactors that might affect PCB blood levels were examined, and it was found that age, sex, and amount of fish consumption (in that order) were the most important (60). PCBs can also be passed from mother to infant through the placenta or breast milk (59,61,62). It seems to be well established that higher exposure to PCBs means a higher blood level of PCBs.…”

Section: Strategy Of Biological Markers: a Measure Of Internal Dosementioning

confidence: 99%

Epidemiologic Approaches to Assessing Human Cancer Risk from Consuming Aquatic Food Resources from Chemically Contaminated Water

Ozonoff¹,

Longnecker²

1991

Environmental Health Perspectives

View full text Add to dashboard Cite

Epidemiologic approaches to human cancer risk fom nung fish from contaminated waters must confront the problems oflong latency and rrity ofthe end point (cancer). The lateIcy prblem makes deter_nation ofdiet history more difficult, while the low frequency ofcancer as an end point reduces the satistcl power ofthe study. These factors are dissed in relation to the study desig most co y emplyed in epideogy. It is sted that the use ofbiomarkers for t is may be useful to mige the difficuly ofdeerngepsure, while the use of more prnt and timely end points, such as carcinogen-DNA adducts or oncogene proteins, may make the latency and rarity problems more tractable.

show abstract

“…Certain couples may wish to obtain information regarding the possible adverse effect of PCBs or dioxins and furans on reproductive outcome and plan future child bearing accordingly. In a related matter, because PCBs and related compounds concentrate in breast milk (as well as pass through the human placenta) questions of breast feeding by the exposed mother arise (26)(27)(28)(29) One question the occupational medicine physician is asked frequently by exposed workers and their families is whether the compounds can be removed from the body, especially if they are found by direct measurement in fat or blood, or indirect measures of exposure and sensitivity, such as elevated liver enzymes or skin changes, etc., to be in the exposed worker.…”

Section: Treatment Of Patientsmentioning

confidence: 99%

Medical surveillance of exposed persons after exposure to PCBs, chlorinated dibenzodioxins and dibenzofurans after PCB transformer or capacitor incidents.

Schecter¹

1985

Environ Health Perspect

View full text Add to dashboard Cite

The panel discussion from the perspective of occupational medicine regarding appropriate medical surveillance after a PCB transformer or capacitor incident is reviewed. A thorough occupational medicine history and physical examination is stressed for any worker or other patient who may have been exposed. Appropriate laboratory tests, including complete blood count with differential, serum chemistries, serial blood PCB determiniations, fat biopsy to estimate furan and dioxin levels, if indicated, pulmonary function tests, chest X-rays, urinalysis including porphyrin measurement, nerve conduction velocity testing and other tests are discussed. No consensus was reached on recommended length of medical followup.Because the field is rapidly changing, yearly updates of medical protocols are warranted. In addition, the need for surveillance to be conducted by specialists with training and experience in the fields of occupational medicine and nursing was emphasized. It was stressed that measuring the chemicals and their levels in soot and air and then comparing these with the patient's blood or fat levels, in the case of PCBs, furans and dioxins, is vital. It was noted that at present no modality of treatment is known to be clinically efficacious in removing PCBs, furans and dioxins from tissues or blood.

show abstract

Polychlorinated biphenyl contamination of nursing mothers' milk in Michigan.

Abstract: The problem of environmental contamination by toxic substances and human exposure to these substances has attracted increased attention

Cited by 62 publications

References 30 publications

Environmental contaminants in human milk

Environmental contaminants in human milk

Epidemiologic Approaches to Assessing Human Cancer Risk from Consuming Aquatic Food Resources from Chemically Contaminated Water

Medical surveillance of exposed persons after exposure to PCBs, chlorinated dibenzodioxins and dibenzofurans after PCB transformer or capacitor incidents.

Contact Info

Product

Resources

About