Polyarteritis in Children

An Uncommon Clinical Sign in Mucocutaneous Lymph Node Syndrome

“…While the diagnosis of SLE can easily be excluded here (7), PAN cannot be distinguished from MCLS on clinical grounds alone (8,9). PAN usually occurs under one year or between 6 and 16 years of age (10). The high incidence of death by coronary artery lesions is the hallmark of PAN under one year but PAN in the older child is characterized by the involvement of many organs (I I).…”

An Uncommon Clinical Sign in Mucocutaneous Lymph Node Syndrome

“…While the diagnosis of SLE can easily be excluded here (7), PAN cannot be distinguished from MCLS on clinical grounds alone (8,9). PAN usually occurs under one year or between 6 and 16 years of age (10). The high incidence of death by coronary artery lesions is the hallmark of PAN under one year but PAN in the older child is characterized by the involvement of many organs (I I).…”

Polyarteritis nodosa in childhood

“…It is important to separate the patients with MCLS because this illness seems to be most appropriately treated with salicylates (23). In contrast, some children with CPN (8,24,25) and IPN (9,lO) have responded to corticosteroid and immunosuppressive therapy, so the prompt recognition of these illnesses may well be life-saving.…”

Polyarteritis Nodosa: Old Disease, New Etiologies

“…Mild diffuse interstitial myocarditis can be caused by focal necrosis [100]. Among pediatric patients with PAN, cases of hemopericardium have been described [101][102][103]. In terms of vascular manifestations, large vessels can be affected due to necrosis of the vasa vasorum [104].…”

An Uncommon Clinical Sign in Mucocutaneous Lymph Node Syndrome

“…While the diagnosis of SLE can easily be excluded here (7), PAN cannot be distinguished from MCLS on clinical grounds alone (8,9). PAN usually occurs under one year or between 6 and 16 years of age (10). The high incidence of death by coronary artery lesions is the hallmark of PAN under one year but PAN in the older child is characterized by the involvement of many organs (I I).…”

Polyarteritis nodosa in childhood

“…It is important to separate the patients with MCLS because this illness seems to be most appropriately treated with salicylates (23). In contrast, some children with CPN (8,24,25) and IPN (9,lO) have responded to corticosteroid and immunosuppressive therapy, so the prompt recognition of these illnesses may well be life-saving.…”

Polyarteritis Nodosa: Old Disease, New Etiologies

“…Mild diffuse interstitial myocarditis can be caused by focal necrosis [100]. Among pediatric patients with PAN, cases of hemopericardium have been described [101][102][103]. In terms of vascular manifestations, large vessels can be affected due to necrosis of the vasa vasorum [104].…”

An Uncommon Clinical Sign in Mucocutaneous Lymph Node Syndrome

“…While the diagnosis of SLE can easily be excluded here (7), PAN cannot be distinguished from MCLS on clinical grounds alone (8,9). PAN usually occurs under one year or between 6 and 16 years of age (10). The high incidence of death by coronary artery lesions is the hallmark of PAN under one year but PAN in the older child is characterized by the involvement of many organs (I I).…”

Polyarteritis nodosa in childhood

“…It is important to separate the patients with MCLS because this illness seems to be most appropriately treated with salicylates (23). In contrast, some children with CPN (8,24,25) and IPN (9,lO) have responded to corticosteroid and immunosuppressive therapy, so the prompt recognition of these illnesses may well be life-saving.…”

Polyarteritis Nodosa: Old Disease, New Etiologies

“…Mild diffuse interstitial myocarditis can be caused by focal necrosis [100]. Among pediatric patients with PAN, cases of hemopericardium have been described [101][102][103]. In terms of vascular manifestations, large vessels can be affected due to necrosis of the vasa vasorum [104].…”