Poly(L-lactide) implants in repair of defects of the orbital floor: An animal study

Orbital floor reconstruction with poly-l/d-lactide implants: clinical, radiological and immunohistochemical study in sheep

“…This resorption most likely occurs too early and, hence, the plate cannot tolerate the pressure caused by the orbital content. This also supports the results by ROZEMA et al 18 . Because polylactic acid is not osteoconductive, the individual healing potential seems to affect more than the reconstruction method.…”

Orbital floor reconstruction with poly-l/d-lactide implants: clinical, radiological and immunohistochemical study in sheep

“…This resorption most likely occurs too early and, hence, the plate cannot tolerate the pressure caused by the orbital content. This also supports the results by ROZEMA et al 18 . Because polylactic acid is not osteoconductive, the individual healing potential seems to affect more than the reconstruction method.…”

Late degradation simulation of poly(I-Lactide)

“…The early tissue response to the pre-degraded PLLA powder, comprising fibroblasts, histiocytes and lymphocytes, was similar to several studies on PLLA [5,6,25,47] and also on other ~-hydroxy-acids [7,9,20,25,28].…”

Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor

“…Since then, several reports have been published on the use of polylactic implants in reconstruction of orbital walls. 9,10 Inflammatory reactions were not present, whereas there is a similar report published by Rozema et al 9 Reconstructing orbital floor, Lieger et al 11 used P(L/DL)LA 70/ 30 implants. During postoperative period, there were no clinical reactions to foreign body or inflammations.…”

“…The authors emphasize that such implants could successfully replace bone transplants and nonresorptive aloplastic materials. [9][10][11] Accordingly, the results of this study show that none of the patients reconstructed with individually designed PDLLA implants experienced complications such as edema, infection, or implant rejection. Before the surgical procedure, all 10 patients suffered from diplopia that disappeared in 6 patients after orbital floor reconstruction.…”

Orbital floor reconstruction with poly-l/d-lactide implants: clinical, radiological and immunohistochemical study in sheep

“…This resorption most likely occurs too early and, hence, the plate cannot tolerate the pressure caused by the orbital content. This also supports the results by ROZEMA et al 18 . Because polylactic acid is not osteoconductive, the individual healing potential seems to affect more than the reconstruction method.…”

Late degradation simulation of poly(I-Lactide)

“…The early tissue response to the pre-degraded PLLA powder, comprising fibroblasts, histiocytes and lymphocytes, was similar to several studies on PLLA [5,6,25,47] and also on other ~-hydroxy-acids [7,9,20,25,28].…”

Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor

“…Since then, several reports have been published on the use of polylactic implants in reconstruction of orbital walls. 9,10 Inflammatory reactions were not present, whereas there is a similar report published by Rozema et al 9 Reconstructing orbital floor, Lieger et al 11 used P(L/DL)LA 70/ 30 implants. During postoperative period, there were no clinical reactions to foreign body or inflammations.…”

“…The authors emphasize that such implants could successfully replace bone transplants and nonresorptive aloplastic materials. [9][10][11] Accordingly, the results of this study show that none of the patients reconstructed with individually designed PDLLA implants experienced complications such as edema, infection, or implant rejection. Before the surgical procedure, all 10 patients suffered from diplopia that disappeared in 6 patients after orbital floor reconstruction.…”

Orbital floor reconstruction with poly-l/d-lactide implants: clinical, radiological and immunohistochemical study in sheep

“…This resorption most likely occurs too early and, hence, the plate cannot tolerate the pressure caused by the orbital content. This also supports the results by ROZEMA et al 18 . Because polylactic acid is not osteoconductive, the individual healing potential seems to affect more than the reconstruction method.…”

Late degradation simulation of poly(I-Lactide)

“…The early tissue response to the pre-degraded PLLA powder, comprising fibroblasts, histiocytes and lymphocytes, was similar to several studies on PLLA [5,6,25,47] and also on other ~-hydroxy-acids [7,9,20,25,28].…”

Application of Computer-Aided Designing and Rapid Prototyping Technologies in Reconstruction of Blowout Fractures of the Orbital Floor

“…Since then, several reports have been published on the use of polylactic implants in reconstruction of orbital walls. 9,10 Inflammatory reactions were not present, whereas there is a similar report published by Rozema et al 9 Reconstructing orbital floor, Lieger et al 11 used P(L/DL)LA 70/ 30 implants. During postoperative period, there were no clinical reactions to foreign body or inflammations.…”

“…The authors emphasize that such implants could successfully replace bone transplants and nonresorptive aloplastic materials. [9][10][11] Accordingly, the results of this study show that none of the patients reconstructed with individually designed PDLLA implants experienced complications such as edema, infection, or implant rejection. Before the surgical procedure, all 10 patients suffered from diplopia that disappeared in 6 patients after orbital floor reconstruction.…”