Poly I:C induces Mx transcription and promotes an antiviral state against sole aquabirnavirus in the flatfish Senegalese sole (Solea senegalensis Kaup)

Temperature-dependent regulation of gene expression in poly (I:C)-treated Japanese flounder, Paralichthys olivaceus

“…Based on these observations, it can be speculated that temperature influences expression profiles of interferon-related genes. In addition, previous reports showed that high levels of Mx expression could undergo a rapid decrease thereafter [10,41,43]. Consistent with these results, we observed a dramatic decrease of Mx expression at 24 hpi when the fish were reared at 25 C.…”

Immunological responses of turbot (Psetta maxima) to nodavirus infection or polyriboinosinic polyribocytidylic acid (pIC) stimulation, using expressed sequence tags (ESTs) analysis and cDNA microarrays

“…It is possible that our use of an IM route of injection rather than IP and/or higher pIC doses per unit of body weight may be responsible for the large increase in Mx expression reported in this study. However IP injection of 15 mg kg À 1 pIC resulted in large significant increases in Mx expression as early as 12 HPI in Senegalese sole (Solea senegalensis) [52]. Following IM infection with nodavirus marked increases in Mx expression have been reported in sea bream (Sparus aurata L.) and sea bass (Dicentrarchus labrax) at 1 DPI [53].…”

Mx expression in gilthead sea bream (Sparus aurata L.) in response to poly I:C, bacterial LPS and chromosomal DNA: Preliminary study

“…This agrees with the results obtained with Senegalese sole [20], but not with those showed for Atlantic salmon [12], where a peak was obtained at 6 d and 9 d post-inoculation depending on the temperature. Other authors found a peak at 2 d [19], and at 24 h [21]. Therefore, it could serve as a good immunostimulant at very short notice or for treating predictable disease outbreaks.…”