2016
DOI: 10.1161/circulationaha.116.023956
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Abstract: URL: http://www.clinicaltrials.gov. Unique identifier: NCT02200419.

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Cited by 226 publications
(65 citation statements)
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References 43 publications
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“…Fifteen trials that randomised a total of 8737 participants met the inclusion criteria and were included in the analysis. 112,129,[135][136][137][138][139][140][141][142][143][144][145][146][147] Two of the included studies were published in abstract form. 139,144 The two review authors (GJM, GFS) were in agreement on the selection of included studies.…”
Section: Resultsmentioning
confidence: 99%
See 2 more Smart Citations
“…Fifteen trials that randomised a total of 8737 participants met the inclusion criteria and were included in the analysis. 112,129,[135][136][137][138][139][140][141][142][143][144][145][146][147] Two of the included studies were published in abstract form. 139,144 The two review authors (GJM, GFS) were in agreement on the selection of included studies.…”
Section: Resultsmentioning
confidence: 99%
“…5 NO. 17 multicentre trial that enrolled 7402 participants in 12 Canadian hospitals and which was published in 2016, 129 we assessed important clinical outcomes including mortality, kidney injury, stroke and prolonged respiratory support and we summarised the evidence using the GRADE approach.…”
Section: Aims and Objectivesmentioning
confidence: 99%
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“…The MEA platelet function analyzer ADP‐test and ASPI‐test results measures platelet dysfunction associated with P2Y 12 blockers and aspirin, respectively 28. The EXTEM maximum clot firmness ‐ FIBTEM maximum clot firmness and TRAP‐test results were selected to measure global platelet dysfunction function 11, 16. Test results were incorporated into predictive models for CCB as continuous variable.…”
Section: Methodsmentioning
confidence: 99%
“…Several small, single‐center, randomized controlled trials (RCTs) in cardiac surgery have shown that when compared to conventional laboratory testing or clinician judgement alone, near‐patient testing reduced transfusion of RBC10, 11 or non‐RBC blood components 10, 11, 12, 13, 14, 15. In a multicenter RCT of more than 7400 patients, implementation of a blood management algorithm incorporating near‐patient tests, resulted in reduced RBC transfusion, platelet transfusion and overall bleeding 16. In this trial, near‐patient test results were used to direct targeted treatments for coagulopathy only in patients who had already developed severe bleeding 16…”
Section: Introductionmentioning
confidence: 99%