2007
Pneumocystis carinii Pneumonia in Infant Treated With Oral Steroids for Hemangioma
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Cited by 33 publications
(10 citation statements)
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“…PCP has also been documented in pediatric patients with infantile hemangioma during treatment with prednisolone ranging from 5 weeks to 5 months. 15,16 It is thus possible, if not likely, that steroid therapy was a contributing factor to the development of PCP in our patient.…”
Section: Discussionmentioning
confidence: 86%
“…PCP has also been documented in pediatric patients with infantile hemangioma during treatment with prednisolone ranging from 5 weeks to 5 months. 15,16 It is thus possible, if not likely, that steroid therapy was a contributing factor to the development of PCP in our patient.…”
Section: Discussionmentioning
confidence: 86%
“…Adverse effects of high‐dose steroids are several and include significant adrenal suppression and growth retardation, immune suppression, hypertension, bone demineralization, etc . Additional compromise of the infant’s developing immune system by systemic corticosteroid therapy is a concern as demonstrated by recent case reports of life‐threatening Pneumocystis carinii pneumonia infections in infants treated for hemangiomas . Furthermore, approximately 30% of hemangiomas do not respond to corticosteroids.…”
Section: Discussionmentioning
confidence: 99%
“…5 Additional compromise of the infant's developing immune system by systemic corticosteroid therapy is a concern as demonstrated by recent case reports of life-threatening Pneumocystis carinii pneumonia infections in infants treated for hemangiomas. 6 Furthermore, approximately 30% of hemangiomas do not respond to corticosteroids. Vincristine has been used as a second choice in the treatment of complicated hemangiomas not responding to systemic corticosteroids.…”
Section: Treatmentmentioning
confidence: 99%
“…It has also been described as the leading origin of death in such patients. It occurs mainly when there is a defect in T-helper cell (CD 4 ) especially when its count is less than 200 cell per cubic millimeter, PCP can occur in any patients with non-AIDs immunosuppression state 21,22 .…”
Section: What Is Pneumocystis Pneumonia?mentioning
confidence: 99%
