Pneumocystis carinii Infection in the Middle Ear

An unusual case of Pneumocystis carinii presenting as an aural mass

“…Therapy is continued for up to 28 days. In all cases of aural polyps and mastoiditis there was complete resolution of signs and symptoms (Coulman et al, 1987;Breda et al, 1988;Gherman et al, 1988;Smith et al, 1988;Park et al, 1992). The case we present showed more extensive and destructive disease than any previously reported.…”

“…Of these, only 10 cases of otic P. carinii, have been documented in HIV-infected patients (Wasserman and Haghighi, 1992). All patients have been male, aged between 29 and 38 and HIV-positive (Park et al, 1992). If a patient is HIV antibody positive and has an opportunistic infection, he will fit the Centers for Disease Control criteria for AIDS (Schinella et al, 1987).…”

<i>Pneumocystis carinii</i> Infection of the Middle Ear and External Auditory Canal

“…Although most cases do not report destruction of bone on CT scan imaging, there are cases where destruction of the ossicles or bony borders of the middle ear has been documented [8]. All reported cases of otic PC infection respond well to oral or intravenous antiprotozoal agents such as trimethoprim-sulfamethoxazole (co-trimoxazole), and dapsone with complete resolution of signs and symptoms [4,[6][7][8][9]. None of the reported cases required exploration of the os petrosum.…”

Acquired Immunodeficiency Syndrome with Massive Aspergillus Fumigatus Infection

“…Many investigators have reported otologic manifestations in patients with AIDS, but most such studies have been clinical 2–8 . Although insight into the pathogenesis of otologic findings in AIDS can be provided by histopathologic studies of the temporal bone, there have been only five such reports to date 9–13 .…”