PLG and FMRFamide — Endogenous peptides with marked inhibitory effects on opioid-induced feeding

Tyr‐MIF‐1 attenuates antinociceptive responses induced by three models of stress‐analgesia

“…MIF-I, a related peptide, also has been found to reduce warm-water swim-induced antinociception (Galina & Kastin, 1985). This paper adds further support to the concept that MIF-1/Tyr-MIF-1 peptides have opiate antagonist actions (Galina & Kastin, 1985;Kavaliers & Hirst, 1985;Tesky & Kavaliers, 1985) and are part of an antiopiate system that may function to balance the opiate system (Kastin et al, 1979;Galina & Kastin, 1986).…”

Tyr‐MIF‐1 attenuates antinociceptive responses induced by three models of stress‐analgesia

“…MIF-I, a related peptide, also has been found to reduce warm-water swim-induced antinociception (Galina & Kastin, 1985). This paper adds further support to the concept that MIF-1/Tyr-MIF-1 peptides have opiate antagonist actions (Galina & Kastin, 1985;Kavaliers & Hirst, 1985;Tesky & Kavaliers, 1985) and are part of an antiopiate system that may function to balance the opiate system (Kastin et al, 1979;Galina & Kastin, 1986).…”

Opioid and anti‐opioid peptides

“…MIF-1 and Tyr-MIF-1 have been shown to reduce exogenous opioid-induced analgesia in rodents (in the tail flick and scratching tests, Datta et al, Kastin et al, 1979Kastin et al, , 1984Kastin et al, , 1985, goldfish (Ehrensing et al, 1982), and man (in the cold pressor test , Ehrensing et a l , 1984). MIF-1 also decreases opioid-induced ingestive behaviour (Kavaliers and Hirst, 1985c;Olson et al, 1980) and hypothermia (Yehuda et al, 1980).…”

Tyr‐MIF‐1 attenuates antinociceptive responses induced by three models of stress‐analgesia

“…MIF-I, a related peptide, also has been found to reduce warm-water swim-induced antinociception (Galina & Kastin, 1985). This paper adds further support to the concept that MIF-1/Tyr-MIF-1 peptides have opiate antagonist actions (Galina & Kastin, 1985;Kavaliers & Hirst, 1985;Tesky & Kavaliers, 1985) and are part of an antiopiate system that may function to balance the opiate system (Kastin et al, 1979;Galina & Kastin, 1986).…”

Opioid and anti‐opioid peptides

“…MIF-1 and Tyr-MIF-1 have been shown to reduce exogenous opioid-induced analgesia in rodents (in the tail flick and scratching tests, Datta et al, Kastin et al, 1979Kastin et al, , 1984Kastin et al, , 1985, goldfish (Ehrensing et al, 1982), and man (in the cold pressor test , Ehrensing et a l , 1984). MIF-1 also decreases opioid-induced ingestive behaviour (Kavaliers and Hirst, 1985c;Olson et al, 1980) and hypothermia (Yehuda et al, 1980).…”

Tyr‐MIF‐1 attenuates antinociceptive responses induced by three models of stress‐analgesia

“…MIF-I, a related peptide, also has been found to reduce warm-water swim-induced antinociception (Galina & Kastin, 1985). This paper adds further support to the concept that MIF-1/Tyr-MIF-1 peptides have opiate antagonist actions (Galina & Kastin, 1985;Kavaliers & Hirst, 1985;Tesky & Kavaliers, 1985) and are part of an antiopiate system that may function to balance the opiate system (Kastin et al, 1979;Galina & Kastin, 1986).…”

Opioid and anti‐opioid peptides

“…MIF-1 and Tyr-MIF-1 have been shown to reduce exogenous opioid-induced analgesia in rodents (in the tail flick and scratching tests, Datta et al, Kastin et al, 1979Kastin et al, , 1984Kastin et al, , 1985, goldfish (Ehrensing et al, 1982), and man (in the cold pressor test , Ehrensing et a l , 1984). MIF-1 also decreases opioid-induced ingestive behaviour (Kavaliers and Hirst, 1985c;Olson et al, 1980) and hypothermia (Yehuda et al, 1980).…”