Pleural liposarcoma presenting with respiratory distress and suspected diaphragmatic hernia

Carroll, Francis; Kramer, Marshall D.; Acinapura, Anthony J.; Tietjen, Patricia A.; Wagner, Ira; Oiseth, Stanley J.; Smith, Fred B.

doi:10.1016/0003-4975(92)90102-a

Cited by 15 publications

(16 citation statements)

References 4 publications

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“…[1][2][3][4][5][6][7][8][9][10] Some patients are asymptomatic and most are diagnosed by routine chest radiography showing large mass shadows. Symptoms include chest pain, dyspnea, cough, and compression syndrome caused by compression of adjacent organs.…”

Section: Discussionmentioning

confidence: 99%

Primary liposarcoma of the mediastinum

Mase

Kawawaki

Narumiya

et al. 2002

Jpn J Thorac Caridovasc Surg

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Primary mediastinal liposarcomas are extremely rare malignancies that remain asymptomatic until large and, even then, initial symptoms are nonspecific. We report a 48-year-old man followed up for asymptomatic multiple bullae who suffered progressive weight loss and dyspnea on exertion. Radiography and computed tomography of the chest showed a large mass with calcified nodules in the left pleural cavity and giant bullae in the right pleural cavity. Previous computed tomography of the chest showed a small tumor of mediastinal adipose tissue with calcified nodules. Tumor growth was calculated at about 500 times the tumor volume per 3.6 years. We completely resected the mediastinal tumor and conducted a bullectomy through a median sternotomy. The microscopic pathological diagnosis was well-differentiated/sclerosing liposarcoma. The man underwent no postoperative adjunctive irradiation and remains well 8 months after surgery.

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Section: Discussionmentioning

confidence: 99%

Primary liposarcoma of the mediastinum

Mase

Kawawaki

Narumiya

et al. 2002

Jpn J Thorac Caridovasc Surg

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“…Only eight cases have been reported so far. 1,[4][5][6][7] The tumor size and histologic subtype are important prognostic denominators. Based on the histologic criteria, liposarcomas are grouped into four major subtypes that correlate well with the prognosis (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…In order to avoid the danger of local recurrence, the treatment of choice is radical excision. 1 We performed radical resection of the tumor. The postoperative course was uneventful and the patient is currently well and free of the disease 16 months after the operation.…”

Section: Discussionmentioning

confidence: 99%

“…1 They occur mostly in the soft tissues of the lower extremities, retroperitoneum, peritoneum and shoulder region. Primary intrathoracic liposarcomas are, however, very uncommon; Razzak et al 2 in 1971 published 44 such cases, of which 43 originated in the mediastinum and one in the pulmonary hilum.…”

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confidence: 99%

“…Our review of literature revealed eight cases of pleural liposarcoma. 1,[4][5][6][7] We like to add here another indubitable case of well-differentiated pleural liposarcoma.…”

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confidence: 99%

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Primary Pleural Liposarcoma

Batouk

Albdah²,

Agina³

et al. 1995

Ann Saudi Med

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AA Batouk, AM Albdah, HA Agina, AR Khan, Primary Pleural Liposarcoma. 1995; 15(2): 159-161 Liposarcomas are among the most common mesenchymal tumors occurring in adults.1 They occur mostly in the soft tissues of the lower extremities, retroperitoneum, peritoneum and shoulder region. Primary intrathoracic liposarcomas are, however, very uncommon; Razzak et al.2 in 1971 published 44 such cases, of which 43 originated in the mediastinum and one in the pulmonary hilum. These authors, however, did not list any liposarcoma which arose from the pleural surfaces. Later in 1982, Sawamura et al.3 reported seven cases of primary pulmonary liposarcoma. Most of them present within the lung parenchyma. Our review of literature revealed eight cases of pleural liposarcoma.1,4-7 We like to add here another indubitable case of well-differentiated pleural liposarcoma. Case ReportA 55-year-old female presented in the Outpatient Department of King Saud Hospital in Unaiza, Al-Qassim with a history of mild dull aching pain in the right upper chest for the last seven months. She also had mild difficulty in breathing for one month prior to this admission. She was a known case of hypertension and diabetes and had received atenolol (Tenormin) 50 mg once daily and glucophage 500 mg twice daily for the last five years. There was no history of smoking. On physical examination, the blood pressure was 140/70 mm/Hg and the heart rate was 74/min. She was slightly obese with mild shortness of breath. On auscultation, decreased air entry in the right upper lung was noted. The examination of blood revealed hemoglobin concentration to be 11.2 g/dL, white cell count 10.4x10, random blood sugar 7.27 mmol/L. Plasma electrolytes, liver function tests, and blood chemistry were normal. Arterial blood gas analysis was pH 7.345, PCO 2 40.6 mm/Hg, HCO 3 21.7 mm/L, PO 2 69.2 mm/Hg, oxygen saturation 92.3%. Examination of the sputum for acid fast bacilli, neoplastic cells and asbestos bodies was negative. The patient was unable to perform pulmonary function tests. Chest radiograph showed a large well-defined oval opacity in the right upper zone and normal heart size (Figures la and b). A thoracic axial computed tomographic scan showed a well-defined soft tissue mass occupying the apical region of the right hemithorax measuring 5.2x4.5 cm (Figure 2). Bronchoscopy was not considered as the mass was seen on the CT scan outside the lung parenchyma.

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