Pleomorphic liposarcoma of the pectoralis major muscle in an elderly man: Report of a case and review of literature

Abstract

Primary liposarcoma of the pectoral major muscle is extremely rare. We report a case of liposarcoma of the pectoral major muscle which was treated with surgical excision and postoperative radiotherapy. A 70-year-old man admitted with left-sided painless progressively growing breast mass. Radiological investigation revealed liposarcoma of the pectoralis major muscle. The patient was treated by surgical removal. Pathological diagnosis was pleomorphic liposarcoma. The patient had postoperative radiotherapy and free of disease for 9 months. Surgical excision and postoperative radiotherapy is the most favored treatment strategy. Careful follow-up is mandatory for detecting recurrences.

Intramuscular Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma of the Pectoralis Major Masquerading as a Breast Tumor: Management and Review of the Literature

“…Primary liposarcoma of the pectoralis major muscle is an exceedingly rare clinical entity with only a few cases reported in the literature so far. 10,11 However, we were unable to find any cases of ALT/WDL of the pectoralis major muscle presenting as a rapidly growing breast tumor.…”

Thoracic Pleomorphic Liposarcomas: A Prognostic Variability Depending on Location

“…5 It usually comes from the mesenchymal tissue and is localized mainly in the shoulder region, the lower limb, in the retroperitoneal and mesenteric region. 6 It grows locally and invades the neighboring structures as was the case in of our second patient where the invasion was pericardial and myocardial. 7 At mediastinal level, liposarcoma would represent only 1% of all mediastinal tumors.…”

“…6,12 In our first patient, there was a dorsal mass measuring 86mm long. MRI remains the investigation of choice in the parietal locations.…”

Dedifferentiated liposarcoma of the adult male breast

“…Breast liposarcomas have only rarely been found extending into both the stromal tissues and pectoral muscles, and have yet to be described with the dedifferentiated subtype ( 5 , 6 , 7 , 8 , 9 ). This patient presented with significant tumor extension into the stromal tissues and the pectoralis major muscle.…”

“…On imaging studies, liposarcoma subtypes have several common features, although there is a tremendous degree of variation similar to that found on pathological evaluation. Masses on mammography are often very dense and well circumscribed ( 9 , 15 , 16 , 17 ). This patient's well-differentiated component in the breast had a mixed density, and the visualized extent was limited.…”