2020
DOI: 10.1080/09537104.2020.1762852
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Abstract: Coronavirus disease 2019 (COVID-19) is a new infectious disease that currently lacks standardized and established laboratory markers to evaluate its severity. In COVID-19 patients, the number of platelets (PLTs) and dynamic changes of PLT-related parameters are currently a concern. The present paper discusses the potential link between PLT parameters and COVID-19. Several studies have identified a link between severe COVID-19 patients and specific coagulation index, in particular, high D-dimer level, prolonged… Show more

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Cited by 72 publications
(68 citation statements)
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“…Serum sedimentation rates and high sensitivity C-reactive protein are often increased and greater elevations in these markers of inflammation may be associated with disease severity [ 63 , 64 , 65 , 66 ]. Biochemical test results may show an elevated plasma D-dimer level and D-dimer above 1 μg/L is indicative of hypercoagulability and a poor prognostic indicator [ 67 , 68 , 69 , 70 , 71 , 72 ].…”
Section: Laboratory Findings and Imagingmentioning
confidence: 99%
“…Serum sedimentation rates and high sensitivity C-reactive protein are often increased and greater elevations in these markers of inflammation may be associated with disease severity [ 63 , 64 , 65 , 66 ]. Biochemical test results may show an elevated plasma D-dimer level and D-dimer above 1 μg/L is indicative of hypercoagulability and a poor prognostic indicator [ 67 , 68 , 69 , 70 , 71 , 72 ].…”
Section: Laboratory Findings and Imagingmentioning
confidence: 99%
“…Thrombocytopenia is a common complication in severe ill patients with the accompanying risk of developing intravascular coagulopathies resulting in multiple organ damage [3,14,15]. Several studies on COVID-19 infected patients showed the presence of thrombocytopenia [3][4][5][6].…”
Section: Platelet Countmentioning
confidence: 99%
“…The state of procoagulation, which exists in patients with COVID-19, is reflected by the high level of D-dimer, prolonged prothrombin time, and thrombocytopenia 18 , 19 . These thrombi, which exist in COVID-19, are related to both platelet aggregation and thrombin-mediated coagulation.…”
Section: Discussionmentioning
confidence: 99%