Plasmonic sensors based on Metal-insulator-metal waveguides for refractive index sensing applications: A brief review

Kazanskiy, N. L.; Хонина, С. Н.; Butt, Muhammad Ali

doi:10.1016/j.physe.2019.113798

Cited by 196 publications

(80 citation statements)

References 100 publications

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“…Plasmonic sensors have received tremendous attention owing to the label-free process, high sensitivity and fast response [36][37][38]. Plasmonic sensors generate surface plasmons and evanescence field that is sensitive to the changes of refractive index on sensing interfaces [39,40].…”

Section: Plasmonic Sensorsmentioning

confidence: 99%

Advanced Biosensing towards Real-Time Imaging of Protein Secretion from Single Cells

Zhou¹,

Chen²,

Simonian³

2021

Biosensors - Current and Novel Strategies for Biosensing

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Protein secretion of cells plays a vital role in intercellular communication. The abnormality and dysfunction of cellular protein secretion are associated with various physiological disorders, such as malignant proliferation of cells, aberrant immune function, and bone marrow failure. The heterogeneity of protein secretion exists not only between varying populations of cells, but also in the same phenotype of cells. Therefore, characterization of protein secretion from single cell contributes not only to the understanding of intercellular communication in immune effector, carcinogenesis and metastasis, but also to the development and improvement of diagnosis and therapy of relative diseases. In spite of abundant highly sensitive methods that have been developed for the detection of secreted proteins, majority of them fall short in providing sufficient spatial and temporal resolution for comprehensive profiling of protein secretion from single cells. The real-time imaging techniques allow rapid acquisition and manipulation of analyte information on a 2D plane, providing high spatiotemporal resolution. Here, we summarize recent advances in real-time imaging of secretory proteins from single cell, including label-free and labelling techniques, shedding light on the development of simple yet powerful methodology for real-time imaging of single-cell protein secretion.

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Section: Plasmonic Sensorsmentioning

confidence: 99%

Advanced Biosensing towards Real-Time Imaging of Protein Secretion from Single Cells

Zhou¹,

Chen²,

Simonian³

2021

Biosensors - Current and Novel Strategies for Biosensing

View full text Add to dashboard Cite

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“…Several sensor designs based on SWG WGs are proposed in previous studies, which include ring resonators [ 15 ], grating [ 16 ] or photonic crystal [ 17 ]. Besides, there are other highly sensitive plasmonic sensor designs based on metal-insulator-metal WGs also presented [ 18 , 19 , 20 , 21 ]. The sensitivity of such devices is determined by the interaction between the electric field and the ambient medium, which can be improved by increasing the light–matter interaction.…”

Section: Introductionmentioning

confidence: 99%

Subwavelength Grating Double Slot Waveguide Racetrack Ring Resonator for Refractive Index Sensing Application

Kazanskiy

Хонина

Butt

2020

Sensors

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In this paper, a racetrack ring resonator design based on a subwavelength grating double slot waveguide is presented. The proposed waveguide scheme is capable of confining the transverse electric field in the slots and the gaps between the grating segments. This configuration facilitates a large light–matter interaction which elevates the sensitivity of the device approximately 2.5 times higher than the one that can be obtained via a standard slot waveguide resonator. The best sensitivity of the design is obtained at 1000 nm/RIU by utilizing a subwavelength grating double slot waveguide of period 300 nm. The numerical study is conducted via 2D and 3D finite element methods. We believe that the proposed sensor design can play an important role in the realization of highly sensitive lab-on-chip sensors.

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“…A traditional plasmonic MIM waveguide consists of the straight waveguides and the resonance cavities [ 20 , 21 ]. Taking advantage of MIM waveguides, various plasmonic devices can be designed and manufactured [ 22 , 23 , 24 , 25 , 26 , 27 , 28 ]. Recently, cavity resonance formed in MIM waveguides to obtain wavelength filtering and refractive index sensing functions has been investigated by theoretical estimations and experimental verifications [ 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 ].…”

Section: Introductionmentioning

confidence: 99%

Ultrawide Bandgap and High Sensitivity of a Plasmonic Metal-Insulator-Metal Waveguide Filter with Cavity and Baffles

et al. 2020

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A plasmonic metal-insulator-metal waveguide filter consisting of one rectangular cavity and three silver baffles is numerically investigated using the finite element method and theoretically described by the cavity resonance mode theory. The proposed structure shows a simple shape with a small number of structural parameters that can function as a plasmonic sensor with a filter property, high sensitivity and figure of merit, and wide bandgap. Simulation results demonstrate that a cavity with three silver baffles could significantly affect the resonance condition and remarkably enhance the sensor performance compared to its counterpart without baffles. The calculated sensitivity (S) and figure of merit (FOM) in the first mode can reach 3300.00 nm/RIU and 170.00 RIU−1. Besides, S and FOM values can simultaneously get above 2000.00 nm/RIU and 110.00 RIU−1 in the first and second modes by varying a broad range of the structural parameters, which are not attainable in the reported literature. The proposed structure can realize multiple modes operating in a wide wavelength range, which may have potential applications in the on-chip plasmonic sensor, filter, and other optical integrated circuits.

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Plasmonic sensors based on Metal-insulator-metal waveguides for refractive index sensing applications: A brief review

Cited by 196 publications

References 100 publications

Advanced Biosensing towards Real-Time Imaging of Protein Secretion from Single Cells

Advanced Biosensing towards Real-Time Imaging of Protein Secretion from Single Cells

Subwavelength Grating Double Slot Waveguide Racetrack Ring Resonator for Refractive Index Sensing Application

Ultrawide Bandgap and High Sensitivity of a Plasmonic Metal-Insulator-Metal Waveguide Filter with Cavity and Baffles

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