Plasmid diversity of multi-drug-resistant<i>Escherichia coli</i>isolated from children with diarrhoea in a poultry-farming area in Kenya

Kariuki, Samuel; Cf, Gilks; Kimari, J.; Muyodi, Jane; Waiyaki, Peter; Ca, Hart

doi:10.1080/00034983.1997.11813115

Cited by 18 publications

(21 citation statements)

References 24 publications

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“…MDR E. coli isolates have frequently been reported in animals 2,12,16 and animal products 28 in Kenya. Drug resistance is mediated by genes located on chromosome, 15 plasmids, transposons, 38 and/or integrons.…”

Section: Discussionmentioning

confidence: 99%

Streptomycin and Chloramphenicol Resistance Genes inEscherichia coliIsolates from Cattle, Pigs, and Chicken in Kenya

Kikuvi

Schwarz

Ombui

et al. 2007

Microbial Drug Resistance

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The aims of this study were to determine the genetic basis of streptomycin and chloramphenicol resistance in 30 Escherichia coli isolates from food animals in Kenya and the role of plasmids in the spread of the resistance. Seven of the 29 streptomycin-resistant isolates harbored both the strA and strB genes. Twenty-one of isolates had the strA, strB, and aadA1 genes. The strA gene was disrupted by a functional trimethoprim gene, dfrA14 in 10 of the 21 isolates harboring the three streptomycin resistance genes. Physical linkage of intact strA and sul2 genes was found in two different plasmids from four isolates. Linkage of cassette-borne aadA1 and dfrA1 genes in class 1 integrons was found in two of the isolates. Chloramphenicol resistance was due to the gene catA1 in all the chloramphenicol resistant isolates. The strB, strA, and catA1 genes were transferable by conjugation and this points to the significance of conjugative resistance plasmids in the spread and persistence of streptomycin and chloramphenicol resistance in food animals in Kenya.

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Section: Discussionmentioning

confidence: 99%

Streptomycin and Chloramphenicol Resistance Genes inEscherichia coliIsolates from Cattle, Pigs, and Chicken in Kenya

Kikuvi

Schwarz

Ombui

et al. 2007

Microbial Drug Resistance

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“…Other studies have also demonstrated a clear relationship between antibiotic usage and the inevitable rise in resistance especially among gut-related pathogens [21,22], thus emphasizing the need for prudent use of antibiotics which in several studies has been shown to delay emergence and minimise resistance levels to antibiotics [23,24]. Previous studies in Kenya [25] showed that tetracycline was commonly used among poultry farmers and this may also contribute to the overall resistance pool in he community. However, usage of other commonly available classes of antimicrobials in livestock farming in Kenya was minimal and the corresponding resistance levels of E. coli isolates from animals were less than 10% for ampicillin, chloramphenicol, gentamicin, nalidixic acid and cotrimoxazole.…”

Section: Discussionmentioning

confidence: 99%

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et al. 2006

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“…Other investigations have revealed that farm animals are a potential reservoir of antibiotic resistant bacteria [13,14]. In contrast, some authors [15,16,17] have reported that the antibiotic resistance transfer between animals and humans was limited because animal strains colonizing the alimentary tract less readily than human ones. However, the actual impact of antibiotic resistance bacteria isolated from workers who are in frequent contact with animals is not well known.…”

Section: Introductionmentioning

confidence: 94%

Antimicrobial resistance pattern of Escherichia coli strains isolated from poultry farmers and poultry slaughterers in Morocco

Abdellah¹,

Fouzia²

2018

int. arab. j antimicrob. agents

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Aim: The objective of this study is to characterize the antibiotic resistance pattern of Escherichia coli isolates from the fecal samples of poultry workers (farmers and slaughterers), and to study the possible dissemination of resistant E. coli from poultry to humans. Methods:Sixty-four E. coli strains isolated from the fecal samples of poultry workers (33 from poultry farmers and 31 from poultry slaughterers) and 35 isolates from a control group workers were tested for antibiotic resistance by agar disk diffusion with 11 antimicrobial agents. Results:Resistance of E. coli isolated from poultry workers to tetracycline, ampicillin and norfloxacin were significantly (p < 0.05) higher than those isolated from the control group. All E. coli isolates were susceptible to cefotaxime, and most of them are susceptible to gentamicin, amikacin, cefoxitin and ertapenem. Multidrug resistance is alarmingly high in all groups, but was highest in poultry farmers isolates (84%) and poultry slaughterers isolates (80%). Approximately 25% of the E. coli isolates from poultry workers showed resistance to four or more antibiotics.

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Plasmid diversity of multi-drug-resistantEscherichia coliisolated from children with diarrhoea in a poultry-farming area in Kenya

Cited by 18 publications

References 24 publications

Streptomycin and Chloramphenicol Resistance Genes inEscherichia coliIsolates from Cattle, Pigs, and Chicken in Kenya

Streptomycin and Chloramphenicol Resistance Genes inEscherichia coliIsolates from Cattle, Pigs, and Chicken in Kenya

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Antimicrobial resistance pattern of Escherichia coli strains isolated from poultry farmers and poultry slaughterers in Morocco

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