volume 5, issue 12, P925-938 2013
DOI: 10.18632/aging.100624
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Kira S. Sheinerman, Vladimir G. Tsivinsky, Laila Abdullah, Fiona Crawford, Samuil R. Umansky

Abstract: A minimally invasive test for early detection and monitoring of Alzheimer's and other neurodegenerative diseases is a highly unmet need for drug development and planning of patient care. Mild Cognitive Impairment (MCI) is a syndrome characteristic of early stages of many neurodegenerative diseases. Recently, we have identified two sets of circulating brain-enriched miRNAs, the miR-132 family (miR-128, miR-132, miR-874) normalized per miR-491-5p and the miR-134 family (miR-134, miR-323-3p, miR-382) normalized p…

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