1980
DOI: 10.1001/archpsyc.1980.01780230018002
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Plasma Free and Conjugated MHPG in Psychiatric Patients

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Cited by 37 publications

(5 citation statements)
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“…There was no correlation between plasma MHPG and the hostile-suspicious factor score on BPRS, a result already found by Redmond et al (30) for CSF. Likewise, no correlation was traced between MHPG and the hebephrenic factor score on BPRS, which bears out the data of previous studies (8,36,37). A positive correlation (NS) was observed between MHPG and the paranoid factor score on BPRS, which points to the same direction as that of Ko et al (8).…”
Section: Discussionsupporting
confidence: 80%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…There was no correlation between plasma MHPG and the hostile-suspicious factor score on BPRS, a result already found by Redmond et al (30) for CSF. Likewise, no correlation was traced between MHPG and the hebephrenic factor score on BPRS, which bears out the data of previous studies (8,36,37). A positive correlation (NS) was observed between MHPG and the paranoid factor score on BPRS, which points to the same direction as that of Ko et al (8).…”
Section: Discussionsupporting
confidence: 80%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…This could explain why we did not find the correlation between plasma MOPEG and age found by Jimerson et al [1981b] and Halbreich et al [1987] in normal subjects. In depressive patients this correlation is not universally agreed [Sweeney et al, 1980;Siever et al, 1986].…”
Section: Discussionmentioning
confidence: 97%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Perhaps the urinary MHPG measure of NE activity is more reliable since it is usually based on a 24-hour sample. Plasma MHPG shows marked diurnal fluc tuation [Swann et al, 1980;Sweeney et al, 1980] as well as large fluctuations in some subjects in 1 -hour periods [Leckman et al, , 1981.…”
Section: Bipolar Affective Disorder Sensation Seeking and Monoaminesmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.