Plasma Cell Mucositis of Oro- and Hypopharynx: A Case Report

Puvanendran, Mark; Lieder, Anja; Issing, W. J.

doi:10.1155/2012/304136

Cited by 13 publications

(21 citation statements)

References 16 publications

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“…Several times, PCM lesions can enter into differential diagnosis with squamous cell carcinoma (SCC) [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22]; in literature, there are cases in which a differential diagnosis was made with oral carcinoma and there is a case report where a SCC arose from a mucosal plasmacytosis [13]. Therefore, a correct diagnosis and adequate management of the disease are essential.…”

Section: Case Reports In Dentistrymentioning

confidence: 99%

An Uncommon Case of Plasma Cell Mucositis of the Tongue in a Young Man

Antonelli

Averta

Diodati

et al. 2020

Case Reports in Dentistry

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Plasma cell mucositis (PCM) is an unusual plasma cell proliferative disorder of the upper aerodigestive tract. It is a rare disease, and its etiology is not yet known with variable clinical features. Symptoms include dysphagia, oral pain, and swelling. We described a case of PCM involving the tongue of a 14-year-old man. In the first place, several diagnostic hypotheses were proposed, most of them discarded for incompatibility with blood and laboratory tests. This disease rarely manifests itself on the tongue, especially in young patients with no comorbidities. The management of PCM is mainly aimed at reducing the symptoms, and in our report, the treatment involved the use of systemic prednisone with an improvement of the quality of life. At 1-year follow-up, there was no recurrence of the disease. Many therapeutic treatments are able to stabilize but not able to induce a complete remission. PCM is considered an uncommon benign disorder with a favorable prognosis and should be considered in the differential diagnosis with other inflammatory or neoplastic conditions.

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Section: Case Reports In Dentistrymentioning

confidence: 99%

An Uncommon Case of Plasma Cell Mucositis of the Tongue in a Young Man

Antonelli

Averta

Diodati

et al. 2020

Case Reports in Dentistry

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“…The literature contains reports of PCM giving histological findings from lip, gingiva, hard and soft palate, and pharynx . Our tongue specimen shares histological similarity with Zoon balanitis, and PCM can be considered the oral counterpart of the ‘plasma cellular benign balanopostitis' .…”

Section: Discussionmentioning

confidence: 66%

“…PCM, also termed mucous membrane plasmacytosis or oral papillary plasmocytosis, is a rare, benign, multifocal, plasma‐cell proliferative disorder of the oral cavity and upper digestive tract with a chronic relapsing course. To date, < 30 cases have been reported in the literature, with a mean age of 56 years at diagnosis . Tongue involvement was reported in six cases, with the lesions including nodules, fissures, bright red papillary hyperplasia, cobblestone or velvety appearance, mucosal erythema, and swelling .…”

Section: Discussionmentioning

confidence: 99%

Rare lesion on the tongue

2016

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“…In some reported cases application of corticosteroids resulted in partial [15,16] or complete [13,17] regression. Antibiotics [16] and antifungals [6,18] have also been used to treat PCM. Some of the authors also used destructive therapy: electrocoagulation, surgical excision [12,18], carbon dioxide laser and cryotherapy [19].…”

Section: Discussionmentioning

confidence: 99%

“…Antibiotics [16] and antifungals [6,18] have also been used to treat PCM. Some of the authors also used destructive therapy: electrocoagulation, surgical excision [12,18], carbon dioxide laser and cryotherapy [19]. Topical tacrolimus has been reported to have a beneficial effect in treatment of a plasma cell infiltration of the lower lip [20,21].…”

Section: Discussionmentioning

confidence: 99%

Plasma cell mucositis – a rare differential diagnosis for ulceration of oral mucosa

Błażewicz¹,

Barańska‐Rybak²,

Stawczyk-Macieja³

et al. 2015

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Introduction. Plasma cell mucositis (PCM) is a rare condition consisting of plasma cell infiltrate of the mucous membranes that usually involves the genital epithelium. Less frequently lesions are present in the mouth or upper respiratory tract. The etiology of PCM remains unknown. The lesions may occur in the unchanged epithelium (idiopathic, isolated PCM), on the base of inflammatory skin diseases (lichen planus, lichen sclerosus) or cancer (squamous cell carcinoma).Objective. To present a case and draw attention to PCM as a differential diagnosis of lesions within the oral mucous membrane. Case report. We present a patient with painful erosions and erythematous patches located within the mucous membrane of the palate and cheeks lasting more than 5 months. The diagnosis was based on clinical and histopathological examination. Conclusions. The course of PCM includes periods of exacerbations and remissions. Treatment with antibiotics, antifungal agents, local and systemic corticosteroids, isotretinoin or destructive methods usually provides symptomatic relief but does not lead to lesions regression. STRESZCZENIEWprowadzenie. Plazmocytowe zapalenie błon śluzowych (ang. plasma cell mucositis -PCM) jest rzadką jednostką chorobową charakteryzują-cą się naciekiem plazmocytarnym, najczęściej obejmującym nabłonek zewnętrznych narządów płciowych. Znacznie rzadziej zmiany lokalizują się w obrębie jamy ustnej i górnych dróg oddechowych. Etiologia PCM jest nieznana. Zmiany mogą powstać w nabłonku niezmienionym (idiopatyczne, izolowane PCM), jak również na podłożu innych dermatoz zapalnych (liszaj płaski, liszaj twardzinowy) bądź chorób nowotworowych (rak kolczystokomórkowy). Cel pracy. Przedstawienie przypadku PCM i zwrócenie uwagi na konieczność uwzględniania tej jednostki chorobowej w diagnostyce róż-nicowej zmian zlokalizowanych w obrębie błon śluzowych jamy ustnej. Opis przypadku. Prezentujemy przypadek pacjentki ze zmianami w obrębie błon śluzowych policzków i podniebienia w postaci nawracających od 5 miesięcy nadżerek, zmian rumieniowych i ognisk zbielenia z towarzyszącą bolesnością. Rozpoznanie choroby ustalono na podstawie obrazu klinicznego i wyniku badania histopatologicznego.Plasma cell mucositis -a rare differential diagnosis for ulceration of oral mucosa Plazmocytarne zapalenie błon śluzowych -rzadka diagnostyka różnicowa zmian w obrębie błon śluzowych jamy ustnej

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Plasma Cell Mucositis of Oro- and Hypopharynx: A Case Report

Cited by 13 publications

References 16 publications

An Uncommon Case of Plasma Cell Mucositis of the Tongue in a Young Man

An Uncommon Case of Plasma Cell Mucositis of the Tongue in a Young Man

Rare lesion on the tongue

Plasma cell mucositis – a rare differential diagnosis for ulceration of oral mucosa

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