Am J Dis Child
 1980
DOI: 10.1001/archpedi.1980.02130230048015
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Plasma Adrenocorticotrophic Hormone in Congenital Adrenal Hyperplasia

Stephen LaFranchi1
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Cited by 7 publications

(2 citation statements)
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“…Androstenedione also has a circadian rhythm but the magnitude of variability is less than that seen with 17-OHP [ 16 ] and levels often correlate better with overall CAH control [ 17 ]. Although not routinely used in the management of CAH, ACTH levels have been shown to be a useful adjunct [ 18 ], and as seen in our study, often correlate with other hormone markers of biochemical control.…”
Section: Discussionsupporting
confidence: 58%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Androstenedione also has a circadian rhythm but the magnitude of variability is less than that seen with 17-OHP [ 16 ] and levels often correlate better with overall CAH control [ 17 ]. Although not routinely used in the management of CAH, ACTH levels have been shown to be a useful adjunct [ 18 ], and as seen in our study, often correlate with other hormone markers of biochemical control.…”
Section: Discussionsupporting
confidence: 58%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…We demonstrated that nocturnal administration of the long-acting glucocorticoid dexamethasone given at 1/50th of the total daily hydrocortisone dose more effectively suppresses the morning rise in ACTH and adrenal androgens. While ACTH is not routinely used to monitor therapy in CAH, it has been shown to correlate with other clinical markers of control [23]. From a physiologic perspective, ACTH is the most proximal measurable indicator of the activation of the HPA axis and suppression by exogenous glucocorticoid treatment.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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