Plants and human health in the twenty-first century

Raskin, Ilya; Ribnicky, David M.; Komarnytsky, Slavko; Ilić, Nebojša; Poulev, Alexander; Borisjuk, Nikolai; Brinker, Anita; Moreno, Diego A.; Ripoll, Christophe; Yakoby, Nir; O'Neal, Joseph M.; Cornwell, Teresa; Pastor, Ira S.; Fridlender, Bertold

doi:10.1016/s0167-7799(02)02080-2

Cited by 750 publications

(447 citation statements)

References 66 publications

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“…A few species of lithistid has physiological and ecological traits and biotechnological and ecological uses [23]. These are the largest group of demosponges with polyphyletic nature and are associated with microorganisms [45,48].…”

Section: Introductionmentioning

confidence: 99%

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Lithistid Sponges Derived Compounds and Their Importance in Biological Research - A Review

Abirla

2018

Asian J Pharm Clin Res

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Lithistid sponges have an important source of complex natural compounds with biological activities. The lithistid sponges are of interest to biomedical science because of the great variety of pharmaceutically relevant biological activities of their chemical extracts and are considered as economically important. The compounds identified in these sponges have therapeutic potential and have been frequently hypothesized to contain compounds of bacterial origin. The peptides identified from these lithistid sponges are found to be the sources of antifungal activity. The active agents of these sponges also have cytotoxic and immunosuppressive activities. Many of the cyclic peptides of lithistid represent the anti-HIV activity. The different structure and biological activities of the compounds derived from these sponges have more chemical aspects too.

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Section: Introductionmentioning

confidence: 99%

“…Those chemical compounds evolved to interact efficiently with their biological targets; therefore, they occupy a biologically relevant chemical space and represent validated starting points for drug discovery [24,23]. Almost all of the current natural product-derived therapeutics has terrestrial origins.…”

Section: Introductionmentioning

confidence: 99%

Lithistid Sponges Derived Compounds and Their Importance in Biological Research - A Review

Abirla

2018

Asian J Pharm Clin Res

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“…It is estimated that 25% of all drugs prescribed today are derived from flowering plants [5], [6]. Alkaloids, which form the biggest group of drugs in the modern pharmacopeia [7], are secondary metabolites on which plant growth is not dependent. Drugs extracted from plants, or their semisynthetic analogues, have been successfully used against other protozoan diseases, e.g.…”

Section: Introductionmentioning

confidence: 99%

High antitrypanosomal activity of plant-derived sulphur-containing amides

Astelbauer

Obwaller²,

Raninger

et al. 2010

International Journal of Antimicrobial Agents

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“…Data on prescription drugs dispensed from community pharmacies in the United States from 1959 to 1980 indicate that about 25% contained plant extracts or active compounds derived from plants (Newman et al, 2000). Thus, because natural products are rich sources of biologically active compounds, there has been an increasing interest in the development of new antimicrobial agents from plants in recent years (Raskin et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial, Antifungal, and Cytotoxic Activities ofDistictis buccinatoria.

Rojas

Navarro

Alonso

et al. 2007

Pharmaceutical Biology

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The current study was undertaken to evaluate the in vitro antimicrobial and cytotoxic activity of six crude extracts obtained from the leaves and flowers of Distictis buccinatoria (DC.) A.H. Gentry (Bignoniaceae). Antimicrobial activity was tested against the Gram-positive bacteria Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus faecalis; the Gram-negative bacteria Escherichia coli, Klebsiella pneumoniae, and Salmonella typhi; and the fungi Candida albicans, Trichophyton mentagrophytes, Trichophyton rubrum, and Aspergillus niger. The cytotoxic activity of each extract was determined using two human tumor cell lines in culture, nasopharyngeal carcinoma (KB) and colon carcinoma (HCT-15). The results showed that extracts from D. buccinatoria possess antimicrobial activity against the Gram-positive bacteria and against both dermatophyte fungal species. The strongest antibacterial activity observed was that of the dichloromethane extract prepared from flowers, and the best antifungal activity was demonstrated by the dichloromethane extract from the leaves. The hexane and dichloromethane extracts from the flowers exhibited cytotoxicity against KB cells. These results support the traditional folk medicinal uses of this plant.

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Plants and human health in the twenty-first century

Cited by 750 publications

References 66 publications

Lithistid Sponges Derived Compounds and Their Importance in Biological Research - A Review

Lithistid Sponges Derived Compounds and Their Importance in Biological Research - A Review

High antitrypanosomal activity of plant-derived sulphur-containing amides

Antibacterial, Antifungal, and Cytotoxic Activities ofDistictis buccinatoria.

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