Plantar Infection by &lt;i&gt;Scopulariopsis brevicaulis&lt;/i&gt;

Ginarte, Manuel; Pereiro, Manuel; Fernández‐Redondo, Virginia; Toribio, J.

doi:10.1159/000246234

Cited by 13 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most cases are associated with exposure to sandy beaches in tropical regions, where H. werneckii is found in areas of high salinity (588). However, individual cases due to Scopulariopsis brevicaulis, Phoma eupyrena, and Chaetomium globosum with findings consistent with tinea nigra have also been reported (57,154,287). Diagnosis is made by skin scraping, and biopsy is not needed.…”

Section: Phaeohyphomycosismentioning

confidence: 99%

Melanized Fungi in Human Disease

2010

View full text Add to dashboard Cite

SUMMARY Melanized or dematiaceous fungi are associated with a wide variety of infectious syndromes. Many are soil organisms and are generally distributed worldwide, though certain species appear to have restricted geographic ranges. Though they are uncommon causes of disease, melanized fungi have been increasingly recognized as important pathogens, with most reports occurring in the past 20 years. The spectrum of diseases with which they are associated has also broadened and includes allergic disease, superficial and deep local infections, pneumonia, brain abscess, and disseminated infection. For some infections in immunocompetent individuals, such as allergic fungal sinusitis and brain abscess, they are among the most common etiologic fungi. Melanin is a likely virulence factor for these fungi. Diagnosis relies on careful microscopic and pathological examination, as well as clinical assessment of the patient, as these fungi are often considered contaminants. Therapy varies depending upon the clinical syndrome. Local infection may be cured with excision alone, while systemic disease is often refractory to therapy. Triazoles such as voriconazole, posaconazole, and itraconazole have the most consistent in vitro activity. Further studies are needed to better understand the pathogenesis and optimal treatment of these uncommon infections.

show abstract

Section: Phaeohyphomycosismentioning

confidence: 99%

Melanized Fungi in Human Disease

2010

View full text Add to dashboard Cite

show abstract

“…Very little information exists about the in vitro activity of antifungals against Scopulariopsis. In the majority of reports, only one strain was tested and details about the technique used are generally scarce (1,2,4,5,8,9,11,13,14,20,21). In this study, in vitro antifungal susceptibilities of clinical and environmental isolates of Scopulariopsis spp.…”

mentioning

confidence: 98%

“…Combined with itraconazole, amphotericin B showed good results on three occasions. Itraconazole was also used alone for one patient with ulcerous cheilitis (1) and one with plantar infection (5). The first patient relapsed after a certain degree of improvement, but the second was cured completely after the failure of ketoconazole and fluconazole.…”

mentioning

confidence: 99%

“…are generally contradictory, probably due to the variety of methods used. However, in only six articles were there details of the method employed (5,9,11,14,20,21). In four of the studies the agar dilution method was used, a disc diffusion method was used in another, and a broth dilution method was used in the sixth.…”

mentioning

confidence: 99%

“…They compared three solid media (Sabouraud dextrose agar, yeast malt agar, and Casitone agar) and concluded that S. brevicaulis was highly resistant to griseofulvine, tolnaftate, amphotericin B, and flucytosine and moderately sensitive to miconazole and ketoconazole. More data about the in vitro antifungal susceptibilities of clinical isolates of Scopulariopsis have appeared in some reports of human infections caused by these fungi (1,2,4,5,9,11,13,14,21). Amphotericin B was defined as ineffective every time it was tested (seven times).…”

mentioning

confidence: 99%

See 2 more Smart Citations