Pityriasis Rubra Pilaris

Pityriasis Rubra Pilaris in Childhood: A Long‐term Study of 29 Cases

“…Since PRP has been described as an autosomal dominant disease (15,16,19), it is surprising to us that we have thus far not observed any cases of hereditary disease. Even though some cases appear very convincing (16), others (8,20) have been disputed during the course of dermatology symposia. We agree with Griffiths's conclusion (3) that many cases of hereditary PRP are actually atypical forms of ichthyosis or psoriasis.…”

Original article Pityriasis rubra pilaris-an historical approach. 2 CLINICAL FEATURES

“…In most cases with the onset after the 4th decade the disease lasts between i and 3 years. Gross (1969) reviewing the literature found that j% had cleared and 60" ^ had improved by the time the reports were written. The average duration for the disease was not stated.…”

“…In a series of fifty-eight patients thirty-one were female and twenty-seven were male (Kierland & Kulwin, 1950). Gross (1969) reviewing the Enghsh language literature found sixty-seven females and eighty-three males.…”

“…The age distribution was reported to be bi-modal with peaks in the ist and 5th decades (Kierland & Kulwin, 1950;Davidson et aL, 1969). Both these reports were based on overlapping material drawn from the Mayo clinic, and Gross (1969) in his review of 150 cases failed to demonstrate a preponderance at any age.…”

Pityriasis Rubra Pilar and hypothyroidism

“…The first was in 1964, in a review article. 8 Tunessen et al described the second case of erythrodermic PRP in a 4-year-old child, associated with severe hypothyroidism. 7 The last described case we found was from Orlandini et al, about a 24-year-old man with erythrodermic PRP who presented complete improvement of the clinical picture after 3 months of hormone replacement.…”