2013
DOI: 10.1007/s13671-013-0054-x
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Pityriasis Lichenoides and Cutaneous T Cell Lymphoma: An Update on the Diagnosis and Management of the Most Common Benign and Malignant Cutaneous Lymphoproliferative Diseases in Children

Abstract: Although more common with advanced age, the entire spectrum of benign and malignant cutaneous lymphoproliferative disorders can present in the pediatric population. Nevertheless, these conditions are often mistaken for other more common, benign dermatoses, resulting in delayed diagnosis. Standardized management of these conditions is also lacking. The purpose of this review is to provide an update on the most common benign and malignant cutaneous lymphoproliferative disorders in children: pityriasis lichenoide… Show more

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Cited by 6 publications
(6 citation statements)
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“…4,5) Recent evidence suggested a relationship between PL and MF, categorized into three groups: PL with T- cell infiltration, PL evolving to MF, and PL-like MF. [7][8][9][10] PL-like MF is a rare subtype of MF, described as causing similar benign skin lesions as those of PL but having histopathological findings as those of malignant MF, as illustrated in our case.…”
Section: Discussionmentioning
confidence: 95%
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“…4,5) Recent evidence suggested a relationship between PL and MF, categorized into three groups: PL with T- cell infiltration, PL evolving to MF, and PL-like MF. [7][8][9][10] PL-like MF is a rare subtype of MF, described as causing similar benign skin lesions as those of PL but having histopathological findings as those of malignant MF, as illustrated in our case.…”
Section: Discussionmentioning
confidence: 95%
“…Pityriasis lichenniodes (PL) and MF are traditionally regarded as two different entities, representing the most common benign and malignant lymphoproliferative disorders in children, respectively. 9,10) PL is characterized by reactive cutaneous eruptions of erythematous scaly papules, while MF has a wide range of clinical presentations depending on its variants. Histopathologic findings of PL include necrotic keratinocytes, spongiosis, erythrocyte extravasation, and perivascular cell infiltration.…”
Section: Discussionmentioning
confidence: 99%
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“…FUMHD is a rare acquired dermatosis that presents with erythematous, scaly papules and progresses to widespread necrotic ulcers with systemic symptoms. Systemic manifestations of FUMHD include fever, musculoskeletal pain, gastrointestinal symptoms, central nervous system involvement, megaloblastic anemia, pancytopenia, disseminated intravascular coagulation, interstitial pneumonitis, and myocarditis . Of the few reported cases, roughly half occurred in patients younger than 20 years old, and a strong male predominance was observed .…”
Section: Discussionmentioning
confidence: 99%
“…A rare subtype of MF called pityriasis lichenoides-like MF (PL-like MF) manifests as recurrent crops of erythematous scaly papules with the histological findings of MF [ 1 , 4 ]. Ko et al first described PL-like lesions in three MF patients in 2000 [ 5 ].…”
Section: Introductionmentioning
confidence: 99%