1997
DOI: 10.1001/archderm.133.10.1296
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Pigmentary changes in aged and photoaged skin

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Cited by 29 publications
(27 citation statements)
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“…Unexpectedly, in the sub-groups before 40 years of age, there were more women with no facial pigmented spots in the Chinese sample population. However, in the same age groups, there were also more Chinese women having many pigmented [14][15][16].…”
Section: Discussionmentioning
confidence: 91%
“…Unexpectedly, in the sub-groups before 40 years of age, there were more women with no facial pigmented spots in the Chinese sample population. However, in the same age groups, there were also more Chinese women having many pigmented [14][15][16].…”
Section: Discussionmentioning
confidence: 91%
“…We aimed to measure solar lentigines as a skin aging characteristic, but simultaneously measured seborrheic keratosis (brown warty lesions in elderly). It is unlikely that other types of pigmented facial spots (melanocytic nevi, freckles and melasma (Castanet and Ortonne, 1997;Ezzedine et al, 2012;Maize and Foster, 1979)) have biased our measure because they are more common in young individuals, and we additionally excluded all heavily freckled individuals. Therefore, our pigmented spots phenotype consists of solar lentigines and (a minority of) seborrheic keratosis.…”
Section: Discussionmentioning
confidence: 99%
“…In severely photodamaged skin, there is a loss of polarity (orderly maturation of skin cell layers) and keratinocytes may show atypia. The ratio of melanocyte density is approximately twice that of non-exposed skin 5 . Other profound changes occur in the dermis, where photodamage is characterized by degeneration of collagen and deposition of abnormal elastotic material (Figs 1 and 2).…”
Section: Photoaging-clinical and Histological Characteristicsmentioning
confidence: 89%